Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.40 |
| ▸ | TLR8 | Q9NR97 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 6/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | SMPD1 | P17405 | 4/20 | 0.37 |
| ▸ | IDH1 | O75874 | 1/20 | 0.36 |
| ▸ | IDH2 | P48735 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 6/20 | 0.36 |
| ▸ | RAB9A | P51151 | 6/20 | 0.36 |
| ▸ | APOBEC3A | P31941 | 2/20 | 0.36 |
| ▸ | APOBEC3G | Q9HC16 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 4/20 | 0.36 |
| ▸ | GALR3 | O60755 | 2/20 | 0.35 |
| ▸ | ATM | Q13315 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16592112 | 0.98 | LMNA (0.40) | LMNATLR8HTTKDM4ESMN1; SMN2 | |
| SCHEMBL24309186 | 0.98 | LMNA (0.40) | LMNATLR8HTTKDM4ESMN1; SMN2 | |
| SCHEMBL21210598 | 0.98 | LMNA (0.40) | LMNATLR8HTTKDM4ESMN1; SMN2 | |
| SCHEMBL13270149 | 0.95 | LMNA (0.41) | LMNATLR8HTTKDM4ESMN1; SMN2 | |
| SCHEMBL15417666 | 0.87 | LMNA (0.43) | LMNAHTTKDM4ESMN1; SMN2MAPT | |
| SCHEMBL10569844 | 0.84 | CNR1 (0.40) | LMNAHTTKDM4ESMN1; SMN2MAPT | |
| SCHEMBL13249108 | 0.81 | POLB (0.38) | LMNAHTTKDM4ESMN1; SMN2MAPT | |
| SCHEMBL31010218 | 0.80 | IRAK4 (0.43) | LMNAHTTKDM4ESMN1; SMN2MAPT | |
| SCHEMBL950089 | 0.80 | LMNA (0.45) | LMNAHTTKDM4ESMN1; SMN2MAPT | |
| SCHEMBL5632040 | 0.77 | POLB (0.39) | LMNAHTTKDM4ESMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10023532-B2 | Alkyl phenyl sulfide derivative and pest control agent | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2018-07-17 | — | — | US | disclosed |
| US-9332754-B2 | Alkyl phenyl sulfide derivative and pest control agent | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2016-05-10 | — | — | US | disclosed |
| US-20150087833-A1 | ALKYL PHENYL SULFIDE DERIVATIVE AND PEST CONTROL AGENT | IHARA CHEMICAL INDUSTRY CO., LTD. (JP) | 2015-03-26 | — | — | US | disclosed |
| CN-102977027-A | Preparation method of 5-aryl-3-trifluoromethyl-1H-pyrazole compound | UNIV TIANJIN | 2013-03-20 | — | — | CN | disclosed |
| EP-2501407-A1 | ANTI-ORAI1 ANTIGEN BINDING PROTEINS AND USES THEREOF | Amgen Inc. (US) | 2012-09-26 | — | — | EP | disclosed |
| US-20120231006-A1 | ANTI-ORAI1 ANTIGEN BINDING PROTEINS AND USES THEREOF | AMGEN INC. (US) | 2012-09-13 | — | — | US | disclosed |
| WO-2011063277-A1 | ANTI-ORAI1 ANTIGEN BINDING PROTEINS AND USES THEREOF | AMGEN INC. (US) | 2011-05-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120231006-A1 | ANTI-ORAI1 ANTIGEN BINDING PROTEINS AND USES THEREOF | STIM2, ORAI2, STIM1 | LMNA 2498/4885TLR8 3025/4885HTT 3840/4885 |
| US-20150087833-A1 | ALKYL PHENYL SULFIDE DERIVATIVE AND PEST CONTROL AGENT | C1S, TRPA1, STK39 | LMNA 4259/4885TLR8 2805/4885HTT 1595/4885 |
| US-10023532-B2 | Alkyl phenyl sulfide derivative and pest control agent | C1S, TRPA1, STK39 | LMNA 4259/4885TLR8 2805/4885HTT 1595/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.