Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | GMNN | O75496 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | THPO | P40225 | 1/20 | 0.40 |
| ▸ | MTOR | P42345 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CETP | P11597 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | UBE2N | P61088 | 1/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8108726 | 0.90 | SPHK1 (0.61) | SPHK1CYP2D6GMNNLMNAPOLB | |
| SCHEMBL16078657 | 0.90 | SPHK1 (0.61) | SPHK1CYP2D6GMNNLMNAPOLB | |
| SCHEMBL16078645 | 0.90 | SPHK1 (0.61) | SPHK1CYP2D6GMNNLMNAPOLB | |
| SCHEMBL16078693 | 0.90 | SPHK1 (0.61) | SPHK1CYP2D6GMNNLMNAPOLB | |
| SCHEMBL16078651 | 0.90 | SPHK1 (0.61) | SPHK1CYP2D6GMNNLMNAPOLB | |
| SCHEMBL16078685 | 0.90 | SPHK1 (0.61) | SPHK1CYP2D6GMNNLMNAPOLB | |
| SCHEMBL11667055 | 0.86 | SPHK1 (0.48) | SPHK1CYP2D6GMNNLMNAPOLB | |
| SCHEMBL31314066 | 0.86 | SPHK1 (0.48) | SPHK1CYP2D6GMNNLMNAPOLB | |
| SCHEMBL3148122 | 0.85 | SPHK1 (0.56) | SPHK1CYP2D6GMNNLMNAPOLB | |
| SCHEMBL4235679 | 0.83 | LMNA (0.44) | SPHK1LMNACYP3A4TRPV1TRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 100 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022036506-A1 | COMPOSITION AND USE OF SGLT-2 INHIBITOR AND ANGIOTENSIN RECEPTOR BLOCKERS | 天津睿创康泰生物技术有限公司 | 2022-02-24 | — | — | WO | claimed |
| CN-112641773-A | Composition containing heterocyclic compound and use thereof | 黄泳华 | 2021-04-13 | — | — | CN | claimed |
| CN-111265512-A | Composition containing a mixture of benzyl benzene derivatives and uses thereof | 黄泳华 | 2020-06-12 | — | — | CN | claimed |
| CN-103497199-B | Dioxa-bicyclo[3.2.1]octane-2, 3, 4-triol derivatives | PFIZER | 2015-04-29 | — | — | CN | claimed |
| CN-101938902-B | Benzylphenylcyclohexane derivatives and methods of use | THERACOS INC | 2014-07-02 | — | — | CN | claimed |
| CN-102149717-B | Dioxa-bicyclo [3.2.1] octane-2, 3, 4-triol derivatives | PFIZER | 2014-05-14 | — | — | CN | claimed |
| CN-103497199-A | Dioxa-bicyclo[3.2.1]octane-2, 3, 4-triol derivatives | PFIZER | 2014-01-08 | — | — | CN | claimed |
| CN-102149717-A | Dioxa-bicyclo [3.2.1] octane-2, 3, 4-triol derivatives | PFIZER | 2011-08-10 | — | — | CN | claimed |
| US-7550239-B2 | Alkyltriol titanyl phthalocyanine photoconductors | XEROX CORPORATION (US) | 2009-06-23 | — | — | US | claimed |
| US-20080176155-A1 | Alkyltriol titanyl phthalocyanine photoconductors | XEROX CORPORATION | 2008-07-24 | — | — | US | claimed |
| CN-118510877-A | Cleaning composition for pretreatment of metal substrates, method for the production thereof and use thereof | 巴斯夫涂料有限公司 | 2024-08-16 | — | — | CN | disclosed |
| CN-117538468-A | High performance liquid chromatography for detecting Ai Tuoge column purity and impurities thereof | 江苏海悦康医药科技有限公司 | 2024-02-09 | — | — | CN | disclosed |
| CN-113912567-B | Process for preparing glucopyranosyl derivatives and intermediates therefor | 宜昌东阳光长江药业股份有限公司 | 2024-01-16 | — | — | CN | disclosed |
| CN-116789716-A | Preparation method of dapagliflozin and Ai Tuoge gliflozin intermediate | 南京科默生物医药有限公司 | 2023-09-22 | — | — | CN | disclosed |
| US-20230250121-A1 | METHOD FOR PREPARING GLUCOPYRANOSYL DERIVATIVES AND INTERMEDIATES THEREOF | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2023-08-10 | — | — | US | disclosed |
| WO-2010040835-A2 | LIQUID PYRACLOSTROBIN-CONTAINING CROP PROTECTION FORMULATIONS | BASF SE (DE) | 2010-04-15 | — | — | WO | disclosed |
| WO-2010040834-A2 | LIQUID AQUEOUS CROP PROTECTION FORMULATIONS | BASF SE (DE) | 2010-04-15 | — | — | WO | disclosed |
| US-20100086958-A1 | NOVEL ENZYME | ISIS INNOVATION LIMITED (GB) | 2010-04-08 | — | — | US | disclosed |
| US-7550239-B2 | Alkyltriol titanyl phthalocyanine photoconductors | XEROX CORPORATION (US) | 2009-06-23 | — | — | US | disclosed |
| US-20080176155-A1 | Alkyltriol titanyl phthalocyanine photoconductors | XEROX CORPORATION | 2008-07-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230250121-A1 | METHOD FOR PREPARING GLUCOPYRANOSYL DERIVATIVES AND INTERMEDIATES THEREOF | SLC5A2, SLC5A1, UGGT1 | SPHK1 1058/4885CYP2D6 305/4885GMNN 791/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.