Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HCRTR1 | O43613 | 9/20 | 0.36 |
| ▸ | HCRTR2 | O43614 | 9/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL964130 | 0.69 | KDM4E (0.45) | KDM4EHSD17B10USP2HPGDNPSR1 | |
| SCHEMBL22906223 | 0.65 | L3MBTL1 (0.38) | KDM4EUSP2HPGDKMT2AMEN1 | |
| SCHEMBL15108582 | 0.65 | KDM4E (0.62) | KDM4EHSD17B10USP2HPGDNPSR1 | |
| SCHEMBL20976824 | 0.64 | HCRTR1 (0.54) | HCRTR1HCRTR2 | |
| SCHEMBL27452629 | 0.64 | HCRTR1 (0.50) | KDM4EHSD17B10USP2HPGDNPSR1 | |
| SCHEMBL1708189 | 0.63 | KMT2A (0.56) | KDM4EHSD17B10USP2HPGDNPSR1 | |
| SCHEMBL13033934 | 0.63 | KMT2A (0.56) | KDM4EHSD17B10USP2HPGDNPSR1 | |
| SCHEMBL21963537 | 0.63 | HCRTR1 (0.51) | HCRTR1HCRTR2 | |
| SCHEMBL29117985 | 0.63 | HCRTR1 (0.51) | HCRTR1HCRTR2 | |
| SCHEMBL19391639 | 0.62 | ALOX5 (0.44) | KDM4EKMT2AMEN1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2250998-B1 | SKIN WHITENING AGENT AND EXTERNAL PREPARATION FOR THE SKIN | SHISEIDO CO LTD (JP) | 2016-04-13 | — | — | EP | disclosed |