Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.38 |
| ▸ | GAA | P10253 | 4/20 | 0.38 |
| ▸ | G6PD | P11413 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 5/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | GLA | P06280 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.35 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9923533 | 1.00 | L3MBTL1 (0.38) | L3MBTL1GAAG6PDMAPTRAB9A | |
| SCHEMBL4799037 | 0.80 | NAPRT (0.32) | MAPTKDM4EMAOB | |
| SCHEMBL19391639 | 0.79 | ALOX5 (0.44) | GAAMAPTKDM4EALOX5MEN1 | |
| SCHEMBL19507158 | 0.76 | MAPT (0.35) | L3MBTL1GAAG6PDMAPTRAB9A | |
| SCHEMBL14275214 | 0.74 | MAPT (0.34) | L3MBTL1GAAMAPTRAB9AMAPK1 | |
| SCHEMBL22055640 | 0.74 | SMN1; SMN2 (0.40) | MAPTMAPK1KDM4EALDH1A1USP2 | |
| SCHEMBL17677339 | 0.65 | KDM4E (0.39) | L3MBTL1GAAKDM4EALDH1A1USP2 | |
| SCHEMBL7719928 | 0.65 | L3MBTL1 (0.40) | L3MBTL1GAAG6PDMAPTRAB9A | |
| SCHEMBL11050112 | 0.65 | ALDH1A1 (0.46) | L3MBTL1GAAG6PDMAPTRAB9A | |
| SCHEMBL972562 | 0.65 | L3MBTL1 (0.43) | L3MBTL1GAAG6PDMAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020006423-A9 | SYNTHETIC GUIDE MOLECULES, COMPOSITIONS AND METHODS RELATING THERETO | EDITAS MEDICINE, INC. (US) | 2021-01-21 | — | — | WO | disclosed |