Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | CDYL2 | Q8N8U2 | 5/20 | 0.46 |
| ▸ | CDYL | Q9Y232 | 4/20 | 0.46 |
| ▸ | CDY1; CDY1B | Q9Y6F8 | 4/20 | 0.46 |
| ▸ | CBX7 | O95931 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.43 |
| ▸ | HPGD | P15428 | 5/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.42 |
| ▸ | TUBB | P07437 | 2/20 | 0.42 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.42 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.42 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.42 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.42 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17667839 | 0.84 | MAPT (0.44) | MAPTGAAMEN1KMT2ACDYL2 | |
| SCHEMBL1058048 | 0.81 | SMN1; SMN2 (0.47) | MAPTCDYL2CDYLCDY1; CDY1BCBX7 | |
| SCHEMBL1063569 | 0.78 | CDYL2 (0.48) | MAPTKMT2ACDYL2CDYLCDY1; CDY1B | |
| SCHEMBL10314637 | 0.76 | CDYL2 (0.52) | MAPTCDYL2CDYLCDY1; CDY1BCBX7 | |
| SCHEMBL10314590 | 0.73 | SMN1; SMN2 (0.48) | MAPTCDYL2CDYLCDY1; CDY1BCBX7 | |
| SCHEMBL1061180 | 0.72 | SMO (0.56) | MAPTCDYL2CDYLCDY1; CDY1BCBX7 | |
| SCHEMBL14780911 | 0.71 | CA12 (0.42) | MAPTMEN1KMT2ACDYL2CDYL | |
| SCHEMBL1062730 | 0.70 | KMT2A (0.46) | MAPTGAAMEN1KMT2AKDM4E | |
| SCHEMBL1061681 | 0.69 | CXCR3 (0.45) | MAPTGAAMEN1KMT2ACDYL2 | |
| SCHEMBL1056839 | 0.69 | KMT2A (0.49) | MAPTGAAMEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2247588-B1 | FUSED HETEROCYCLIC DERIVATIVE AND USE THEREOF | TAKEDA PHARMACEUTICAL (JP) | 2016-04-13 | — | — | EP | disclosed |