Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CDYL2 | Q8N8U2 | 5/20 | 0.44 |
| ▸ | CDYL | Q9Y232 | 4/20 | 0.44 |
| ▸ | CDY1; CDY1B | Q9Y6F8 | 4/20 | 0.44 |
| ▸ | CBX7 | O95931 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 4/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17677357 | 0.84 | MAPT (0.49) | MAPTMEN1GAAKMT2ACDYL2 | |
| SCHEMBL1058048 | 0.74 | SMN1; SMN2 (0.47) | MAPTCDYL2CDYLCDY1; CDY1BCBX7 | |
| SCHEMBL1063569 | 0.70 | CDYL2 (0.48) | MAPTKMT2ACDYL2CDYLCDY1; CDY1B | |
| SCHEMBL10314637 | 0.68 | CDYL2 (0.52) | MAPTCDYL2CDYLCDY1; CDY1BCBX7 | |
| SCHEMBL1248647 | 0.67 | SMN1; SMN2 (0.65) | MAPTMEN1KMT2ANPC1RAB9A | |
| SCHEMBL15151638 | 0.67 | RAB9A (0.63) | MAPTMEN1GAAKMT2ANPC1 | |
| SCHEMBL10314590 | 0.66 | SMN1; SMN2 (0.48) | MAPTCDYL2CDYLCDY1; CDY1BCBX7 | |
| SCHEMBL14725968 | 0.64 | ELANE (0.50) | MAPTKMT2ACDYL2CDYLCDY1; CDY1B | |
| SCHEMBL15005212 | 0.63 | ALDH1A1 (0.68) | MAPTMEN1GAAKMT2ANPC1 | |
| SCHEMBL9938937 | 0.63 | SMN1; SMN2 (0.59) | MAPTMEN1KMT2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2247588-B1 | FUSED HETEROCYCLIC DERIVATIVE AND USE THEREOF | TAKEDA PHARMACEUTICAL (JP) | 2016-04-13 | — | — | EP | disclosed |