Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 4/20 | 0.47 |
| ▸ | SMO | Q99835 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17677407 | 0.92 | SMO (0.47) | PDE4BSMOLMNA | |
| SCHEMBL1061851 | 0.89 | SMO (0.58) | PDE4BSMONPC1RAB9A | |
| SCHEMBL1061384 | 0.87 | LMNA (0.47) | SMOLMNANPC1RAB9A | |
| SCHEMBL1058238 | 0.87 | LMNA (0.49) | PDE4BLMNANPC1RAB9A | |
| SCHEMBL1061569 | 0.85 | LMNA (0.46) | PDE4BSMOLMNANPC1RAB9A | |
| SCHEMBL1060628 | 0.83 | SMO (0.54) | SMOLMNANPC1RAB9A | |
| SCHEMBL1061487 | 0.83 | SMO (0.56) | PDE4BSMOLMNA | |
| SCHEMBL17677384 | 0.80 | SMO (0.47) | SMOLMNANPC1RAB9A | |
| SCHEMBL27854593 | 0.80 | LMNA (0.51) | LMNANPC1RAB9A | |
| SCHEMBL1062446 | 0.80 | KMT2A (0.50) | SMOLMNANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2247588-B1 | FUSED HETEROCYCLIC DERIVATIVE AND USE THEREOF | TAKEDA PHARMACEUTICAL (JP) | 2016-04-13 | — | — | EP | disclosed |