Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CREBBP | Q92793 | 16/20 | 0.48 |
| ▸ | BRD4 | O60885 | 12/20 | 0.48 |
| ▸ | KIF11 | P52732 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.37 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22368888 | 0.84 | CREBBP (0.66) | CREBBPBRD4 | |
| SCHEMBL22368597 | 0.82 | CREBBP (0.61) | CREBBPBRD4 | |
| SCHEMBL22368642 | 0.81 | CREBBP (0.48) | CREBBPBRD4 | |
| SCHEMBL22369263 | 0.81 | CREBBP (0.48) | CREBBPBRD4 | |
| SCHEMBL17680925 | 0.79 | CREBBP (0.65) | CREBBPBRD4 | |
| SCHEMBL22369015 | 0.78 | CREBBP (0.70) | CREBBPBRD4LMNASMN1; SMN2CRBN | |
| SCHEMBL17680957 | 0.78 | CREBBP (0.65) | CREBBPBRD4SMN1; SMN2 | |
| SCHEMBL17680954 | 0.77 | CREBBP (0.67) | CREBBPBRD4LMNASMN1; SMN2 | |
| SCHEMBL22368776 | 0.77 | CREBBP (0.49) | CREBBPBRD4 | |
| SCHEMBL19539030 | 0.76 | CREBBP (0.63) | CREBBPBRD4LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016055028-A1 | THERAPEUTIC COMPOUNDS AND USES THEREOF | GENENTECH, INC. (US) | 2016-04-14 | — | — | WO | disclosed |
| US-20150147457-A1 | ISOTOPICALLY MODIFIED COMPOUNDS AND THEIR USE AS FOOD SUPPLEMENTS | BIOJIVA LLC | 2015-05-28 | — | — | US | disclosed |