Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 2/20 | 0.37 |
| ▸ | CNR2 | P34972 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LPAR1 | Q92633 | 4/20 | 0.32 |
| ▸ | LPAR3 | Q9UBY5 | 4/20 | 0.32 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19266155 | 0.82 | DNM1 (0.56) | DNM1CNR1CNR2ALDH1A1LPAR1 | |
| SCHEMBL17263914 | 0.82 | DNM1 (0.56) | DNM1CNR1CNR2ALDH1A1LPAR1 | |
| SCHEMBL13445900 | 0.82 | DNM1 (0.56) | DNM1CNR1CNR2ALDH1A1LPAR1 | |
| SCHEMBL11940481 | 0.79 | OPRM1 (0.31) | — | |
| SCHEMBL5532689 | 0.78 | DNM1 (0.61) | DNM1CNR1CNR2ALDH1A1LPAR1 | |
| SCHEMBL18051492 | 0.78 | DNM1 (0.61) | DNM1CNR1CNR2ALDH1A1LPAR1 | |
| SCHEMBL8345191 | 0.78 | DNM1 (0.61) | DNM1CNR1CNR2ALDH1A1LPAR1 | |
| SCHEMBL11187145 | 0.78 | DNM1 (0.61) | DNM1CNR1CNR2ALDH1A1LPAR1 | |
| SCHEMBL11181978 | 0.78 | DNM1 (0.61) | DNM1CNR1CNR2ALDH1A1LPAR1 | |
| SCHEMBL11189857 | 0.78 | DNM1 (0.61) | DNM1CNR1CNR2ALDH1A1LPAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170313643-A1 | PROCESS FOR THE PREPARATION OF TREPROSTINIL | CHINOIN Gyógyszer és Vegyészeti Termékek Gyára Zrt. (HU) | 2017-11-02 | — | — | US | disclosed |
| WO-2016055819-A1 | PROCESS FOR THE PREPARATION OF TREPROSTINIL | CHINOIN Gyógyszer és Vegyészeti Termékek Gyára Zrt. (HU) | 2016-04-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170313643-A1 | PROCESS FOR THE PREPARATION OF TREPROSTINIL | PTGIS, CYP2C19, CYP2F1 | DNM1 1928/4885CNR1 1737/4885CNR2 2834/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.