Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16418024 | 0.86 | — | — | |
| SCHEMBL11952996 | 0.82 | OPRM1 (0.32) | OPRM1 | |
| SCHEMBL8927225 | 0.81 | LMNA (0.42) | OPRM1 | |
| SCHEMBL11940479 | 0.79 | — | — | |
| SCHEMBL17682838 | 0.79 | DNM1 (0.40) | — | |
| SCHEMBL8926627 | 0.79 | DNM1 (0.46) | OPRM1 | |
| SCHEMBL6870580 | 0.76 | DNM1 (0.39) | OPRM1 | |
| SCHEMBL20013254 | 0.74 | OPRM1 (0.34) | OPRM1 | |
| SCHEMBL15547201 | 0.73 | CA2 (0.32) | — | |
| SCHEMBL15547204 | 0.73 | CA2 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11724979-B2 | Process for the preparation of treprostinil | CHINOIN Gyógyszer és Vegyészeti Termékek Gyára Zrt. (HU) | 2023-08-15 | — | — | US | disclosed |
| US-20170313643-A1 | PROCESS FOR THE PREPARATION OF TREPROSTINIL | CHINOIN Gyógyszer és Vegyészeti Termékek Gyára Zrt. (HU) | 2017-11-02 | — | — | US | disclosed |
| US-20170313643-A1 | PROCESS FOR THE PREPARATION OF TREPROSTINIL | CHINOIN Gyógyszer és Vegyészeti Termékek Gyára Zrt. (HU) | 2017-11-02 | — | — | US | disclosed |
| EP-2576492-B1 | TREPROSTINIL PRODUCTION | UNITED THERAPEUTICS CORP (US) | 2017-09-20 | — | — | EP | disclosed |
| WO-2016055819-A1 | PROCESS FOR THE PREPARATION OF TREPROSTINIL | CHINOIN Gyógyszer és Vegyészeti Termékek Gyára Zrt. (HU) | 2016-04-14 | — | — | WO | disclosed |
| US-20150105582-A1 | TREPROSTINIL PRODUCTION | UNITED THERAPEUTICS CORPORATION (US) | 2015-04-16 | — | — | US | disclosed |
| US-20150105582-A1 | TREPROSTINIL PRODUCTION | UNITED THERAPEUTICS CORPORATION (US) | 2015-04-16 | — | — | US | disclosed |
| US-8940930-B2 | Treprostinil production | UNITED THERAPEUTICS CORPORATION (US) | 2015-01-27 | — | — | US | disclosed |
| US-8940930-B2 | Treprostinil production | UNITED THERAPEUTICS CORPORATION (US) | 2015-01-27 | — | — | US | disclosed |
| WO-2014203278-A2 | NOVEL PROCESS FOR THE PREPARATION OF (1R,2R,3aS,9aS)-[[2,3,3a,4,9,9a-HEXAHYDRO-2-HYDROXY-1-[(3S)-3-HYDROXYOCTYL]-1H-BENZ[f]INDEN-5-YL]OXY]ACETIC ACID | MSN LABORATORIES PRIVATE LIMITED (IN) | 2014-12-24 | — | — | WO | disclosed |
| US-8481782-B2 | Treprostinil production | UNITED THERAPEUTICS CORPORATION (US) | 2013-07-09 | — | — | US | disclosed |
| US-8481782-B2 | Treprostinil production | UNITED THERAPEUTICS CORPORATION (US) | 2013-07-09 | — | — | US | disclosed |
| US-20120197041-A1 | TREPROSTINIL PRODUCTION | UNITED THERAPEUTICS CORPORATION | 2012-08-02 | — | — | US | disclosed |
| US-20120190888-A1 | TREPROSTINIL PRODUCTION | UNITED THERAPEUTICS CORPORATION | 2012-07-26 | — | — | US | disclosed |
| US-20110319641-A1 | TREPROSTINIL PRODUCTION | UNITED THERAPEUTICS CORPORATION | 2011-12-29 | — | — | US | disclosed |
| WO-2011153363-A1 | TREPROSTINIL PRODUCTION | UNITED THERAPEUTICS CORPORATION (US) | 2011-12-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120190888-A1 | TREPROSTINIL PRODUCTION | PTGIS, PTGIR, PTGES | OPRM1 3911/4885 |
| US-20150105582-A1 | TREPROSTINIL PRODUCTION | PTGIS, PTGIR, PTGES | OPRM1 3911/4885 |
| US-11724979-B2 | Process for the preparation of treprostinil | PTGIS, TFPI, TREH | OPRM1 739/4885 |
| US-20110319641-A1 | TREPROSTINIL PRODUCTION | PTGIS, PTGIR, PTGES | OPRM1 3738/4885 |
| US-20120197041-A1 | TREPROSTINIL PRODUCTION | PTGIS, PTGIR, PTGES | OPRM1 3911/4885 |
| US-20170313643-A1 | PROCESS FOR THE PREPARATION OF TREPROSTINIL | PTGIS, CYP2C19, CYP2F1 | OPRM1 2860/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.