Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 3/20 | 0.34 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.34 |
| ▸ | BACE1 | P56817 | 3/20 | 0.32 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.32 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.31 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.31 |
| ▸ | PIM1 | P11309 | 1/20 | 0.31 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.31 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.31 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.31 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.31 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.31 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.31 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17688072 | 0.81 | GSK3B (0.33) | TLR7FFAR4TLR9TLR8PIM1 | |
| SCHEMBL17687824 | 0.78 | FFAR4 (0.38) | TLR7FFAR4BACE1PIM1PIM3 | |
| SCHEMBL17687832 | 0.71 | FFAR4 (0.42) | TLR7FFAR4 | |
| SCHEMBL19471844 | 0.71 | FFAR4 (0.42) | TLR7FFAR4 | |
| SCHEMBL17687962 | 0.70 | CYP11B2 (0.39) | CYP11B2CYP11B1 | |
| SCHEMBL17688042 | 0.70 | DYRK1A (0.38) | TLR7FFAR4BACE1PIM1PIM3 | |
| SCHEMBL19471536 | 0.69 | DYRK1A (0.35) | TLR7FFAR4BACE1PIM1PIM3 | |
| SCHEMBL9965911 | 0.68 | CHRNB2 (0.33) | TLR7CHRNB2CHRNB4CHRNA3CHRNA7 | |
| SCHEMBL19471546 | 0.68 | TLR9 (0.34) | TLR7TLR9TLR8PIM1PIM3 | |
| SCHEMBL19464139 | 0.66 | KMO (0.33) | PIM1PIM3PIM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3207042-B1 | ANTIBACTERIAL BASIC BIAROMATIC DERIVATIVES WITH AMINOALKOXY SUBSTITUTION | IDORSIA PHARMACEUTICALS LTD (CH) | 2018-10-03 | — | — | EP | disclosed |
| US-9850256-B2 | Antibacterial basic biaromatic derivatives with aminoalkoxy substitution | IDORSIA PHARMACEUTICALS LTD (CH) | 2017-12-26 | — | — | US | disclosed |
| US-20170305927-A1 | ANTIBACTERIAL BASIC BIAROMATIC DERIVATIVES WITH AMINOALKOXY SUBSTITUTION | IDORSIA PHARMACEUTICALS LTD (CH) | 2017-10-26 | — | — | US | disclosed |
| EP-3207042-A1 | ANTIBACTERIAL BASIC BIAROMATIC DERIVATIVES WITH AMINOALKOXY SUBSTITUTION | Idorsia Pharmaceuticals Ltd (CH) | 2017-08-23 | — | — | EP | disclosed |
| WO-2016059097-A1 | ANTIBACTERIAL BASIC BIAROMATIC DERIVATIVES WITH AMINOALKOXY SUBSTITUTION | ACTELION PHARMACEUTICALS LTD (CH) | 2016-04-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170305927-A1 | ANTIBACTERIAL BASIC BIAROMATIC DERIVATIVES WITH AMINOALKOXY SUBSTITUTION | RPSA, RPL4, RPS4Y1 | TLR7 1315/4885FFAR4 912/4885BACE1 4186/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.