Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.50 |
| ▸ | NOTUM | Q6P988 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 4/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 2/20 | 0.34 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.34 |
| ▸ | HTR3B | O95264 | 1/20 | 0.34 |
| ▸ | HTR3A | P46098 | 1/20 | 0.34 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.34 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
| ▸ | AHR | P35869 | 3/20 | 0.33 |
| ▸ | CRHBP | P24387 | 1/20 | 0.32 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11602314 | 0.80 | NOTUM (0.40) | CYP3A4NOTUMALDH1A1IDO1HTR3E | |
| SCHEMBL10482195 | 0.78 | KDR (0.35) | CYP3A4NOTUMHPGDTSHRALDH1A1 | |
| SCHEMBL10616182 | 0.78 | ALDH1A1 (0.39) | CYP3A4NOTUMTSHRALDH1A1IDO1 | |
| SCHEMBL10695590 | 0.78 | HSD17B10 (0.52) | CYP3A4NOTUMHPGDHSD17B10TSHR | |
| SCHEMBL7855792 | 0.78 | TP53 (0.36) | NOTUMIDO1HTR3EHTR3BHTR3A | |
| SCHEMBL11602223 | 0.77 | NOTUM (0.44) | NOTUMIDO1HTR3EHTR3BHTR3A | |
| SCHEMBL27796545 | 0.77 | ALDH1A1 (0.52) | CYP3A4NOTUMHPGDHSD17B10TSHR | |
| SCHEMBL6417699 | 0.76 | CYP3A4 (0.53) | CYP3A4HPGDHSD17B10TSHRHSP90AA1 | |
| SCHEMBL10554028 | 0.75 | NOTUM (0.36) | NOTUMIDO1HTR3EHTR3BHTR3A | |
| SCHEMBL6222180 | 0.75 | NOTUM (0.43) | CYP3A4NOTUMHPGDTSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 100 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118119583-A | Method for producing fluorine-containing aromatic compound | 大金工业株式会社 | 2024-05-31 | — | — | CN | claimed |
| CN-112174878-B | Method and device for preparing 2, 6-dichloropyridine by fractional photochlorination of pyridine | 浙江埃森化学有限公司 | 2023-05-26 | — | — | CN | claimed |
| CN-112174878-A | Method and device for preparing 2, 6-dichloropyridine by stepwise photochlorination of pyridine | 浙江埃森化学有限公司 | 2021-01-05 | — | — | CN | claimed |
| EP-1272447-B1 | METHOD FOR PRODUCING 2,3,4,5-TETRACHLOROBENZOTRIFLUORIDE | LANXESS DEUTSCHLAND GMBH (DE) | 2005-11-02 | — | — | EP | claimed |
| US-6706934-B2 | Method for producing 2,3,4,5-tetrachlorobenzotrifluoride | BAYER AKTIENGESELLSCHAFT (DE) | 2004-03-16 | — | — | US | claimed |
| US-20030078459-A1 | Method for producing 2,3,4,5-tetrachlorobenzotrifluoride | LANXESS DEUTSCHLAND GMBH (DE) | 2003-04-24 | — | — | US | claimed |
| EP-1272447-A1 | METHOD FOR PRODUCING 2,3,4,5-TETRACHLOROBENZOTRIFLUORIDE | Bayer Aktiengesellschaft (DE) | 2003-01-08 | — | — | EP | claimed |
| WO-2001074746-A1 | METHOD FOR PRODUCING 2,3,4,5-TETRACHLOROBENZOTRIFLUORIDE | BAYER AKTIENGESELLSCHAFT (DE) | 2001-10-11 | — | — | WO | claimed |
| EP-2542531-B1 | PROCESS FOR SYNTHESIS OF FIPRONIL | GHARDA KEKI HORMUSJI (IN) | 2014-09-17 | — | — | EP | disclosed |
| US-8507693-B2 | Process for synthesis of fipronil | Gharda Medical and Advanced Technologies Foundation (IN) | 2013-08-13 | — | — | US | disclosed |
| EP-1528052-B1 | Process for the production of 4-amino-3,5-dichlorobenzotrifluoride with high purity commercial products being obtained in parallel | FINCHIMICA SRL (IT) | 2013-07-31 | — | — | EP | disclosed |
| US-20130030190-A1 | PROCESS FOR SYNTHESIS FIPRONIL | Gharda Medical and Advanced Technologies Foundation (IN) | 2013-01-31 | — | — | US | disclosed |
| EP-2542531-A1 | PROCESS FOR SYNTHESIS OF FIPRONIL | Gharda, Keki Hormusji (IN) | 2013-01-09 | — | — | EP | disclosed |
| CN-102781920-A | Process for synthesizing fipronil | HORMUSJI GHARDA KEKI | 2012-11-14 | — | — | CN | disclosed |
| US-4770688-A | 5-azido- or 5-phosphoroimido-1-arylpyrazoles, composition containing them, and herbicidal and plant growth regulating methods of using them | BAYER AKTIENGESELLSCHAFT (DE) | 1988-09-13 | — | — | US | disclosed |
| US-4758673-A | 1-aryl-5-halopyrazoles | BAYER AKTIENGESELLSCHAFT (DE) | 1988-07-19 | — | — | US | disclosed |
| EP-0150587-B1 | PREPARATION OF CHLOROBENZOTRIFLUORIDE COMPOUNDS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1988-02-03 | — | — | EP | disclosed |
| US-4681618-A | 1-aryl-5-halo-4-nitopyrazoles, herbicidal compositions containing them, and herbicidal method of using them | BAYER AKTIENGESELLSCHAFT (DE) | 1987-07-21 | — | — | US | disclosed |
| EP-0187285-A2 | Process for the preparation of substituted phenyl hydrazines | BAYER AG (DE) | 1986-07-16 | — | — | EP | disclosed |
| EP-0150587-A2 | Preparation of chlorobenzotrifluoride compounds | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1985-08-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130030190-A1 | PROCESS FOR SYNTHESIS FIPRONIL | FIP1L1, CYP2F1, PFAS | CYP3A4 7/4885NOTUM 1796/4885HPGD 1005/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.