SCHEMBL6417699

SCHEMBL6417699

Clc1cc(C(Cl)(Cl)Cl)c(Cl)c(Cl)c1Cl

nearest known ligand 0.53

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 4/20 0.53
TSHR P16473 5/20 0.42
MAPK1 P28482 2/20 0.42
TDP1 Q9NUW8 1/20 0.42
HPGD P15428 4/20 0.42
HSD17B10 Q99714 4/20 0.42
HSP90AA1 P07900 1/20 0.42
ALDH1A1 P00352 2/20 0.36
AHR P35869 5/20 0.34
CRHBP P24387 1/20 0.33
CRHR2 Q13324 1/20 0.33
CASP1 P29466 1/20 0.33
AKR1B1 P15121 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11553083 0.85 CYP3A4 (0.42) CYP3A4TSHRMAPK1TDP1
SCHEMBL11601275 0.79 TSHR (0.44) CYP3A4TSHRMAPK1TDP1HPGD
SCHEMBL1833205 0.77 CYP3A4 (0.38) CYP3A4TSHRMAPK1TDP1ALDH1A1
SCHEMBL1764669 0.77 TSHR (0.38) CYP3A4TSHRMAPK1TDP1
SCHEMBL5650970 0.76 CYP3A4 (0.50) CYP3A4TSHRMAPK1HPGDHSD17B10
SCHEMBL29022408 0.76 ALDH1A1 (0.55) CYP3A4TSHRMAPK1TDP1HPGD
SCHEMBL1768795 0.76 CYP3A4 (0.50) CYP3A4TSHRMAPK1HPGDHSD17B10
SCHEMBL11226916 0.76 TSHR (0.57) CYP3A4TSHRMAPK1TDP1ALDH1A1
SCHEMBL11235301 0.74 TSHR (0.46) CYP3A4TSHRMAPK1TDP1HPGD
SCHEMBL8974765 0.74 CYP3A4 (0.34) CYP3A4TSHRMAPK1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4191711-A Process for the preparation of certain nuclear chlorinated benzotrichlorides BAYER AKTIENGESELLSCHAFT (DE) 1980-03-04 US claimed
CN-112979453-A Preparation method of benzoyl chloride compound 江西仰立新材料有限公司 2021-06-18 CN disclosed
EP-1528052-B1 Process for the production of 4-amino-3,5-dichlorobenzotrifluoride with high purity commercial products being obtained in parallel FINCHIMICA SRL (IT) 2013-07-31 EP disclosed
EP-1528052-A1 Process for the production of 4-amino-3,5-dichlorobenzotrifluoride with high purity commercial products being obtained in parallel FINCHIMICA S.p.A. (IT) 2005-05-04 EP disclosed
EP-0261175-A4 FIBEROUS BATT AND METHOD FOR PRODUCING SUCH. FIBERLOK INC (US) 1988-07-14 EP disclosed
EP-0261175-A1 FIBEROUS BATT AND METHOD FOR PRODUCING SUCH FIBERLOK, INC. (US) 1988-03-30 EP disclosed
CN-87102669-A Fiberboard and manufacture method thereof 1987-12-30 CN disclosed
WO-1987005639-A1 FIBEROUS BATT AND METHOD FOR PRODUCING SUCH FIBERLOK, INC. (US) 1987-09-24 WO disclosed
US-4327036-A FOR AROMATIC NUCLEUS E. I. DU PONT DE NEMOURS AND COMPANY (US) 1982-04-27 US disclosed
US-4191711-A Process for the preparation of certain nuclear chlorinated benzotrichlorides BAYER AKTIENGESELLSCHAFT (DE) 1980-03-04 US disclosed
US-4191711-A Process for the preparation of certain nuclear chlorinated benzotrichlorides BAYER AKTIENGESELLSCHAFT (DE) 1980-03-04 US disclosed
US-4141912-A Process for the preparation of polyhalobenzylic disulfooxonium compounds HOOKER CHEMICALS & PLASTICS CORP. (US) 1979-02-27 US disclosed
US-4075238-A Polyhalobenzylic disulfooxonium compounds HOOKER CHEMICALS & PLASTICS CORPORATION (US) 1978-02-21 US disclosed