Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | PLK1 | P53350 | 1/20 | 0.42 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.42 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.42 |
| ▸ | PARP10 | Q53GL7 | 4/20 | 0.41 |
| ▸ | CHEK2 | O96017 | 3/20 | 0.40 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.40 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NQO2 | P16083 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | CHUK | O15111 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL178439 | 0.82 | ALDH1A1 (0.64) | ALDH1A1SMN1; SMN2PLK1PLA2G10PLA2G2A | |
| SCHEMBL4520699 | 0.77 | CYP17A1 (0.58) | ALDH1A1SMN1; SMN2PLK1PLA2G10PLA2G2A | |
| SCHEMBL10243616 | 0.77 | CYP17A1 (0.58) | ALDH1A1SMN1; SMN2PLK1PLA2G10PLA2G2A | |
| Benzamide SCHEMBL27520826 | 0.73 | L3MBTL1 (0.67) | ALDH1A1SMN1; SMN2PLK1PLA2G10PLA2G2A | |
| SCHEMBL21628385 | 0.73 | PARP10 (0.70) | ALDH1A1SMN1; SMN2PARP10CHEK2 | |
| Trifluoroacetic Acid SCHEMBL7850274 | 0.71 | ALDH1A1 (0.55) | ALDH1A1SMN1; SMN2PLK1PLA2G10PLA2G2A | |
| SCHEMBL28913867 | 0.70 | PLA2G10 (0.48) | ALDH1A1PLA2G10PLA2G2APARP10MAPT | |
| SCHEMBL28913866 | 0.70 | PLA2G10 (0.48) | ALDH1A1PLA2G10PLA2G2APARP10MAPT | |
| SCHEMBL2913661 | 0.70 | HRH3 (0.52) | ALDH1A1PLA2G10PLA2G2APARP10CYP17A1 | |
| SCHEMBL873232 | 0.68 | PRSS1 (0.60) | ALDH1A1PLA2G10PLA2G2APARP10MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3207090-A2 | IMPROVED RUBBER COMPOSITIONS AND USES THEREOF | Bridgestone Corporation (JP) | 2017-08-23 | — | — | EP | disclosed |
| WO-2016061304-A2 | IMPROVED RUBBER COMPOSITIONS AND USES THEREOF | BRIDGESTONE CORPORATION (JP) | 2016-04-21 | — | — | WO | disclosed |