SCHEMBL21628385

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL178439	0.88	ALDH1A1 (0.64)	PARP10PARP15PARP4PARP14ALDH1A1
	SCHEMBL21628632	0.86	PARP10 (0.66)	PARP10PARP15PARP4PARP14ALDH1A1
	SCHEMBL13686078	0.85	ALDH1A1 (0.55)	PARP10PARP15PARP4PARP14ALDH1A1
	SCHEMBL3137816	0.84	PARP10 (1.00)	PARP10PARP15PARP4PARP14ALDH1A1
	SCHEMBL755049	0.83	PARP10 (0.73)	PARP10PARP15PARP4PARP14ALDH1A1
	SCHEMBL680470	0.83	MAPT (0.73)	ALDH1A1KMT2ARXRARXRBMAOB
	SCHEMBL835345	0.83	ALDH1A1 (0.77)	PARP10PARP15ALDH1A1CA1CA2
	SCHEMBL21628604	0.83	PARP10 (0.61)	PARP10PARP15PARP4PARP14ALDH1A1
	SCHEMBL4520699	0.82	CYP17A1 (0.58)	PARP10ALDH1A1CHEK2CA1CA2
	SCHEMBL10243616	0.82	CYP17A1 (0.58)	PARP10ALDH1A1CHEK2CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.