Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRP | O00591 | 4/20 | 0.42 |
| ▸ | GABRD | O14764 | 4/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 4/20 | 0.42 |
| ▸ | GABRB1 | P18505 | 4/20 | 0.42 |
| ▸ | GABRG2 | P18507 | 4/20 | 0.42 |
| ▸ | GABRB3 | P28472 | 4/20 | 0.42 |
| ▸ | GABRA5 | P31644 | 4/20 | 0.42 |
| ▸ | GABRA3 | P34903 | 4/20 | 0.42 |
| ▸ | GABRA2 | P47869 | 4/20 | 0.42 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.42 |
| ▸ | GABRA4 | P48169 | 4/20 | 0.42 |
| ▸ | GABRE | P78334 | 4/20 | 0.42 |
| ▸ | GABRA6 | Q16445 | 4/20 | 0.42 |
| ▸ | GABRG1 | Q8N1C3 | 4/20 | 0.42 |
| ▸ | GABRG3 | Q99928 | 4/20 | 0.42 |
| ▸ | GABRQ | Q9UN88 | 4/20 | 0.42 |
| ▸ | NNMT | P40261 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CPB2 | Q96IY4 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1768859 | 1.00 | GABRP (0.42) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL13719313 | 0.79 | IDH1 (0.43) | NNMTSMN1; SMN2KDM4EALDH1A1GAA | |
| SCHEMBL23722452 | 0.79 | IDH1 (0.43) | NNMTSMN1; SMN2KDM4EALDH1A1GAA | |
| SCHEMBL2272168 | 0.79 | AKR1C3 (0.52) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL2272174 | 0.79 | AKR1C3 (0.52) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| Hydrochloric Acid SCHEMBL2274905 | 0.78 | AKR1C3 (0.50) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL23722448 | 0.77 | PADI4 (0.32) | SMN1; SMN2ALDH1A1 | |
| SCHEMBL16176960 | 0.74 | TUBB4A (0.33) | SMN1; SMN2KDM4EALDH1A1GAACYP2C9 | |
| SCHEMBL16176961 | 0.74 | TUBB4A (0.33) | SMN1; SMN2KDM4EALDH1A1GAACYP2C9 | |
| SCHEMBL1879689 | 0.74 | EGFR (0.34) | SMN1; SMN2KDM4EALDH1A1HDAC1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9321769-B2 | Heterocyclic acrylamides and their use as pharmaceuticals | FAB PHARMA S.A.S. (FR) | 2016-04-26 | — | — | US | disclosed |
| US-20150232466-A1 | NOVEL HETEROCYCLIC ACRYLAMIDES AND THEIR USE AS PHARMACEUTICALS | FAB PHARMA S.A.S. (FR) | 2015-08-20 | — | — | US | disclosed |
| WO-2011061214-A1 | NOVEL HETEROCYCLIC ACRYLAMIDES AND THEIR USE AS PHARMACEUTICALS | FAB PHARMA SAS (FR) | 2011-05-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150232466-A1 | NOVEL HETEROCYCLIC ACRYLAMIDES AND THEIR USE AS PHARMACEUTICALS | ACR, AADAC, AAAS | GABRP 2175/4885GABRD 1514/4885GABRA1 2204/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.