Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | APAF1 | O14727 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4679533 | 0.82 | KMT2A (0.55) | KMT2AGAATSHRLMNARECQL | |
| SCHEMBL2408156 | 0.81 | APAF1 (0.57) | KMT2AALDH1A1LMNASMN1; SMN2CA12 | |
| SCHEMBL2408159 | 0.81 | APAF1 (0.57) | KMT2AALDH1A1LMNASMN1; SMN2CA12 | |
| SCHEMBL6809830 | 0.81 | APAF1 (0.57) | KMT2AALDH1A1LMNASMN1; SMN2CA12 | |
| SCHEMBL8760851 | 0.79 | PTGS2 (0.45) | KMT2AGAATSHRALDH1A1LMNA | |
| SCHEMBL14675504 | 0.74 | KMT2A (0.52) | KMT2AGAATSHRALDH1A1LMNA | |
| SCHEMBL31477970 | 0.74 | KMT2A (0.52) | KMT2ATSHRALDH1A1CA12CA7 | |
| SCHEMBL9545301 | 0.73 | NPC1 (0.44) | TSHRALDH1A1LMNAKDM4E | |
| SCHEMBL8704293 | 0.73 | KMT2A (0.50) | KMT2ATSHRALDH1A1CA12CA7 | |
| SCHEMBL15514630 | 0.73 | KMT2A (0.50) | KMT2AGAATSHRALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2501693-A1 | NOVEL HETEROCYCLIC ACRYLAMIDES AND THEIR USE AS PHARMACEUTICALS | FAB Pharma SAS (FR) | 2012-09-26 | — | — | EP | disclosed |
| WO-2011061214-A1 | NOVEL HETEROCYCLIC ACRYLAMIDES AND THEIR USE AS PHARMACEUTICALS | FAB PHARMA SAS (FR) | 2011-05-26 | — | — | WO | disclosed |