SCHEMBL17690198

SCHEMBL17690198

CCC(C)(C)C(=O)NNC(=O)C(C)C

nearest known ligand 0.45

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
RIPK1 Q13546 4/20 0.37
GAA P10253 1/20 0.33
LMNA P02545 1/20 0.33
POLB P06746 1/20 0.33
KDM4E B2RXH2 1/20 0.32
ALDH1A1 P00352 1/20 0.32
HTT P42858 1/20 0.32
CCR2 P41597 1/20 0.31
MMP8 P22894 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19413865 0.84 RIPK1 (0.45) RIPK1GAALMNAPOLBALDH1A1
SCHEMBL15045362 0.81 RIPK1 (0.38) RIPK1LMNAPOLBALDH1A1CCR2
SCHEMBL26048448 0.78 KDM4E (0.39) GAAKDM4EALDH1A1HTT
SCHEMBL21991816 0.76 RIPK1 (0.42) RIPK1LMNAPOLBHTTMMP8
SCHEMBL17340396 0.74 MEN1 (0.44) RIPK1GAALMNAPOLBALDH1A1
SCHEMBL605889 0.74 GAA (0.48) GAAPOLBKDM4EALDH1A1HTT
SCHEMBL10074651 0.72 EPHX1 (0.43) RIPK1POLBALDH1A1MMP8
SCHEMBL25867844 0.71 CA2 (0.40) GAAPOLBKDM4EALDH1A1HTT
SCHEMBL749946 0.71 RIPK1 (0.47) RIPK1LMNAPOLBALDH1A1CCR2
SCHEMBL13450062 0.71 KMT2A (0.51) LMNAPOLBKDM4EALDH1A1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3009476-A1 POLYMER RESIN COMPOSITION HAVING EXCELLENT CHEMICAL RESISTANCE SK Chemicals Co., Ltd. (KR) 2016-04-20 EP disclosed