SCHEMBL15045362

SCHEMBL15045362

CCC(C)(C)C(=O)NC(=O)C(C)C

nearest known ligand 0.38

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
RIPK1 Q13546 4/20 0.38
LMNA P02545 1/20 0.33
POLB P06746 1/20 0.33
CCR2 P41597 1/20 0.32
MMP8 P22894 1/20 0.31
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14428590 0.81 RIPK1 (0.45) RIPK1LMNAPOLBCCR2ALDH1A1
SCHEMBL17690198 0.81 RIPK1 (0.37) RIPK1LMNAPOLBCCR2MMP8
SCHEMBL21991816 0.78 RIPK1 (0.42) RIPK1LMNAPOLBMMP8
SCHEMBL26719629 0.77 ALDH1A1 (0.40) LMNAALDH1A1
SCHEMBL14997672 0.75 RIPK1 (0.41) RIPK1LMNAPOLBCCR2ALDH1A1
SCHEMBL12017039 0.75 RIPK1 (0.41) RIPK1LMNAPOLBCCR2ALDH1A1
SCHEMBL14838796 0.75 RIPK1 (0.46) RIPK1LMNAPOLBCCR2ALDH1A1
SCHEMBL10074651 0.74 EPHX1 (0.43) RIPK1POLBMMP8ALDH1A1
SCHEMBL749946 0.73 RIPK1 (0.47) RIPK1LMNAPOLBCCR2MMP8
SCHEMBL15045366 0.73 RIPK1 (0.40) RIPK1LMNAPOLBCCR2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8778595-B2 Resist composition, method of forming resist pattern, and polymeric compound TOKYO OHKA KOGYO CO., LTD. (JP) 2014-07-15 US disclosed
US-20130157201-A1 RESIST COMPOSITION, METHOD OF FORMING RESIST PATTERN, AND POLYMERIC COMPOUND TOKYO OHKA KOGYO CO., LTD. (JP) 2013-06-20 US disclosed