Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 4/20 | 0.44 |
| ▸ | HRH1 | P35367 | 4/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.43 |
| ▸ | HTR2C | P28335 | 2/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.43 |
| ▸ | DRD3 | P35462 | 2/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.43 |
| ▸ | HTR2B | P41595 | 2/20 | 0.43 |
| ▸ | KLF10 | Q13118 | 2/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6262528 | 0.81 | ACP3 (0.41) | HTR2AHRH1SLC6A4SLC6A2CYP3A4 | |
| SCHEMBL7980729 | 0.80 | MMP2 (0.49) | CYP3A4CYP2D6CYP1A2TSHRTP53 | |
| SCHEMBL5156714 | 0.80 | P2RX7 (0.42) | CYP1A2TSHRACP3ALDH1A1CTSA | |
| SCHEMBL4450825 | 0.80 | HTR2A (0.60) | HTR2AHRH1SLC6A4SLC6A2CYP3A4 | |
| SCHEMBL10976123 | 0.79 | CNR2 (0.42) | CYP3A4KMT2AACP3ALDH1A1SMN1; SMN2 | |
| SCHEMBL1857873 | 0.78 | ACP3 (0.43) | CYP3A4CYP1A2TSHRKMT2AACP3 | |
| SCHEMBL1928791 | 0.78 | ACP3 (0.43) | CYP3A4CYP1A2TSHRLMNAKMT2A | |
| SCHEMBL20564111 | 0.77 | CYSLTR2 (0.46) | CYP2D6CYP1A2SLC6A3TSHRACP3 | |
| SCHEMBL11291328 | 0.76 | CYSLTR2 (0.45) | ALDH1A1 | |
| SCHEMBL20563923 | 0.76 | CYSLTR2 (0.42) | CYP2D6CYP1A2SLC6A3TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2492262-B1 | FUSED HETEROCYCLIC COMPOUND AND THROMBOPOIETIN RECEPTOR ACTIVATOR | NISSAN CHEMICAL IND LTD (JP) | 2016-04-20 | — | — | EP | disclosed |