Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PREP | P48147 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL770306 | 0.82 | DRD2 (0.40) | PREPALDH1A1TSHR | |
| SCHEMBL771621 | 0.79 | GNAI3 (0.37) | PREPALDH1A1 | |
| SCHEMBL15224167 | 0.73 | ALDH1A1 (0.40) | ALDH1A1TSHR | |
| SCHEMBL770812 | 0.70 | NPC1 (0.41) | ALDH1A1TSHR | |
| SCHEMBL771510 | 0.69 | PRMT5 (0.33) | — | |
| SCHEMBL12985461 | 0.69 | PAOX (0.33) | — | |
| SCHEMBL15224165 | 0.68 | TSHR (0.37) | ALDH1A1TSHR | |
| SCHEMBL11072154 | 0.67 | ABL1 (0.38) | ALDH1A1 | |
| SCHEMBL11072203 | 0.67 | ABL1 (0.38) | ALDH1A1 | |
| SCHEMBL770944 | 0.67 | DRD2 (0.49) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2439202-B1 | INHIBITOR COMPOUNDS OF 11-BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 1 | SALVAT LAB SA (ES) | 2016-04-20 | — | — | EP | disclosed |