Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | BDKRB2 | P30411 | 2/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | ITGB1 | P05556 | 6/20 | 0.42 |
| ▸ | ITGA5 | P08648 | 6/20 | 0.42 |
| ▸ | ITGB3 | P05106 | 4/20 | 0.42 |
| ▸ | ITGAV | P06756 | 4/20 | 0.42 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.41 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.41 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.41 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.41 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.41 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ITGB5 | P18084 | 3/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30054860 | 0.92 | ABCB1 (0.44) | ABCB1POLBBDKRB2HTR2CITGB1 | |
| SCHEMBL18569430 | 0.92 | ABCB1 (0.44) | ABCB1POLBBDKRB2HTR2CITGB1 | |
| SCHEMBL16402973 | 0.92 | ABCB1 (0.44) | ABCB1POLBBDKRB2HTR2CITGB1 | |
| SCHEMBL6319947 | 0.87 | POLB (0.45) | POLBHTR2CPSEN1PSEN2APH1B | |
| SCHEMBL17691469 | 0.87 | ABCB1 (0.41) | ABCB1POLBBDKRB2HTR2CITGB1 | |
| SCHEMBL116032 | 0.84 | BDKRB2 (0.47) | ABCB1BDKRB2ITGB1ITGA5ITGB3 | |
| SCHEMBL16402902 | 0.84 | ITGB1 (0.42) | ABCB1BDKRB2ITGB1ITGA5ITGB3 | |
| SCHEMBL3980427 | 0.84 | ABCB1 (0.45) | ABCB1POLBHTR2CITGB1ITGA5 | |
| SCHEMBL3902022 | 0.84 | ABCB1 (0.45) | ABCB1POLBHTR2CITGB1ITGA5 | |
| SCHEMBL6803097 | 0.84 | POLB (0.43) | POLBHTR2CPSEN1PSEN2APH1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160108027-A1 | SUBSTITUTED BENZOXAZOLES | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2016-04-21 | — | — | US | disclosed |
| US-20160108039-A1 | TRIAZOLOPYRIDINES AS THROMBIN INHIBITORS FOR THE TREATMENT OF THROMBOEMBOLIC DISEASES | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2016-04-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160108027-A1 | SUBSTITUTED BENZOXAZOLES | TBXA2R, XDH, CYP4X1 | ABCB1 134/4885POLB 2395/4885BDKRB2 187/4885 |
| US-20160108039-A1 | TRIAZOLOPYRIDINES AS THROMBIN INHIBITORS FOR THE TREATMENT OF THROMBOEMBOLIC DISEASES | PLAT, TFPI, SERPINC1 | ABCB1 488/4885POLB 2767/4885BDKRB2 203/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.