SCHEMBL176946

SCHEMBL176946

N#Cc1ccc(O)cc1F

nearest known ligand 0.57

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
TRPV4 Q9HBA0 2/20 0.57
ESR1 P03372 6/20 0.51
ESR2 Q92731 6/20 0.51
AR P10275 5/20 0.49
CYP11B1 P15538 7/20 0.44
CYP11B2 P19099 7/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31122790 0.98 TRPV4 (0.55) TRPV4ESR1ESR2ARCYP11B1
Alcohol SCHEMBL27852105 0.90 TRPV4 (0.48) TRPV4ESR1ESR2ARCYP11B1
4-Cyanophenol SCHEMBL6894396 0.90 CA9 (0.59) TRPV4ESR1ESR2ARCYP11B1
SCHEMBL29025457 0.84 ESR1 (0.44) TRPV4ESR1ESR2ARCYP11B1
SCHEMBL2786094 0.84 AR (0.62) TRPV4ESR1ESR2ARCYP11B1
SCHEMBL28395061 0.83 CYP11B2 (0.59) CYP11B1CYP11B2
SCHEMBL189517 0.82 ESR1 (0.49) TRPV4ESR1ESR2AR
SCHEMBL17672811 0.81 CA12 (0.47) TRPV4ESR1ESR2ARCYP11B1
SCHEMBL6864959 0.81 TRPV4 (0.47) TRPV4ESR1ESR2ARCYP11B1
SCHEMBL7904754 0.79 AR (0.40) TRPV4ESR1ESR2AR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1573 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115395114-B Preparation method of lithium battery anode lithium supplementing additive 上海交通大学 2025-04-11 CN claimed
CN-118702085-A Method for regulating specific surface area of carbon material 三明学院 2024-09-27 CN claimed
CN-118486919-A Preparation method of sodium supplement additive for positive electrode of sodium battery 上海交通大学 2024-08-13 CN claimed
CN-117264226-A Spherical copper-based metal organic frame electrode material and preparation method thereof 九江学院 2023-12-22 CN claimed
CN-117050922-B Fluorine-containing benzonitrile compound degrading bacterium and application thereof in environmental treatment 江苏聚庚科技股份有限公司 2023-12-08 CN claimed
CN-117050922-A Fluorine-containing benzonitrile compound degrading bacterium and application thereof in environmental treatment 江苏聚庚科技股份有限公司 2023-11-14 CN claimed
CN-116178685-A LCP material with high clearing point and preparation method thereof 宁夏清研高分子新材料有限公司 2023-05-30 CN claimed
CN-115395114-A Preparation method of lithium supplement additive for lithium battery anode 上海交通大学 2022-11-25 CN claimed
CN-111668481-B Preparation method of metal aluminum secondary battery with multi-group organic micromolecules as positive electrode 北京科技大学 2021-12-03 CN claimed
CN-111668481-A Preparation method of metal aluminum secondary battery with multi-group organic micromolecules as positive electrode 北京科技大学 2020-09-15 CN claimed
CN-1730469-A Novel LCD compound p-n-heptyloxy cinnamic acid -2-fluoro-4-hydroxy- benzonitrile ester and its preparation method UNIV QINGDAO SCIENCE & TECHNOLOGY (CN) 2006-02-08 CN claimed
CN-1730472-A Novel LCD compound p-n-pentoxy cinnamic acid -2-fluoro-4-hydroxy- benzonitrile ester and its preparation method UNIV QINGDAO SCIENCE & TECHNOLOGY (CN) 2006-02-08 CN claimed
CN-1730466-A Novel LCD compound p-phenyl-methoxy cinnamic acid -2-fluoro-4-hydroxy- benzonitrile ester and its preparation method UNIV QINGDAO SCIENCE & TECHNOLOGY (CN) 2006-02-08 CN claimed
US-6150390-A ACCELERATES BONE FORMATION; OSTEOPOROSIS; (LTB-4(LEUKOTRIENE-B-4; 5,12-DIHYDROXYEICOSATETRA-6,8,10,14-ENOIC ACID) RECEPTOR ANTAGONIST DONG WHA PHARM. IND. CO., LTD. (KR) 2000-11-21 US claimed
EP-1019384-A1 3-AMINO-1,2-BENZOISOXAZOLE DERIVATIVES, PROCESS FOR PREPARATION, AND USE THEREOF DONG WHA PHARMACEUTICAL INDUSTRIAL CO. LTD. (KR) 2000-07-19 EP claimed
CN-1244196-A 3-amino-1, 2-benzisoxazole derivatives, process for their preparation and their use DONG WHA PHARM CO LTD (KR) 2000-02-09 CN claimed
WO-1998033779-A1 3-AMINO-1,2-BENZOISOXAZOLE DERIVATIVES, PROCESS FOR PREPARATION, AND USE THEREOF DONG WHA PHARM. IND. CO., LTD. (KR) 1998-08-06 WO claimed
EP-0464648-B1 4-Cyano-3-fluorophenyl esters HOFFMANN LA ROCHE (CH) 1995-12-06 EP claimed
EP-0464648-A1 4-Cyano-3-fluorophenyl esters F. HOFFMANN-LA ROCHE AG (CH) 1992-01-08 EP claimed
EP-0241338-B1 MESOMORPHOUS POLYMERS WITH HIGHLY DIELECTRICAL ANISOTROPIE LATERAL CHAINS, AND PROCESS FOR THEIR PREPARATION THOMSON-CSF (FR) 1990-09-05 EP claimed