Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | HPGD | P15428 | 4/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | AIP | O00170 | 1/20 | 0.47 |
| ▸ | SGTA | O43765 | 1/20 | 0.47 |
| ▸ | TOMM70 | O94826 | 1/20 | 0.47 |
| ▸ | STIP1 | P31948 | 1/20 | 0.47 |
| ▸ | PPP5C | P53041 | 1/20 | 0.47 |
| ▸ | DNAJC7 | Q99615 | 1/20 | 0.47 |
| ▸ | STUB1 | Q9UNE7 | 1/20 | 0.47 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17189283 | 0.78 | ALDH1A1 (0.72) | ALDH1A1MAPTHPGDGAAAIP | |
| SCHEMBL8293361 | 0.73 | PTPN1 (0.69) | ALDH1A1MAPTHPGDAIPSGTA | |
| SCHEMBL1067537 | 0.70 | ALDH1A1 (0.80) | ALDH1A1MAPTHPGDGAAAIP | |
| SCHEMBL14478808 | 0.67 | ALDH1A1 (1.00) | ALDH1A1MAPTHPGDGAAAIP | |
| SCHEMBL19444686 | 0.65 | MAPT (0.53) | ALDH1A1MAPTHPGDGAAAIP | |
| SCHEMBL5453282 | 0.63 | AIP (0.71) | ALDH1A1MAPTHPGDAIPSGTA | |
| SCHEMBL5451446 | 0.63 | AIP (0.71) | ALDH1A1MAPTHPGDAIPSGTA | |
| SCHEMBL5460515 | 0.62 | AIP (0.69) | ALDH1A1MAPTHPGDAIPSGTA | |
| SCHEMBL15259283 | 0.62 | PTPN1 (0.66) | AIPSGTATOMM70STIP1PPP5C | |
| SCHEMBL5739664 | 0.60 | PTGER4 (0.42) | ALDH1A1MAPTHPGDGAAAIP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160108102-A1 | Novel GLP-1 Derivatives | NOVO NORDISK AS (DK) | 2016-04-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160108102-A1 | Novel GLP-1 Derivatives | GLP1R, GIPR, IAPP | ALDH1A1 3523/4885MAPT 4364/4885HPGD 3091/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.