Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.72 |
| ▸ | MAPT | P10636 | 10/20 | 0.72 |
| ▸ | HPGD | P15428 | 8/20 | 0.72 |
| ▸ | GAA | P10253 | 2/20 | 0.72 |
| ▸ | AIP | O00170 | 1/20 | 0.53 |
| ▸ | SGTA | O43765 | 1/20 | 0.53 |
| ▸ | TOMM70 | O94826 | 1/20 | 0.53 |
| ▸ | STIP1 | P31948 | 1/20 | 0.53 |
| ▸ | PPP5C | P53041 | 1/20 | 0.53 |
| ▸ | DNAJC7 | Q99615 | 1/20 | 0.53 |
| ▸ | STUB1 | Q9UNE7 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.51 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1067537 | 0.89 | ALDH1A1 (0.80) | ALDH1A1MAPTHPGDGAAAIP | |
| SCHEMBL14478808 | 0.84 | ALDH1A1 (1.00) | ALDH1A1MAPTHPGDGAAAIP | |
| SCHEMBL15533574 | 0.81 | MAPT (0.78) | ALDH1A1MAPTHPGDGAAKDM4E | |
| SCHEMBL17697371 | 0.78 | ALDH1A1 (0.50) | ALDH1A1MAPTHPGDGAAAIP | |
| SCHEMBL8293361 | 0.78 | PTPN1 (0.69) | ALDH1A1MAPTHPGDAIPSGTA | |
| SCHEMBL3498811 | 0.78 | ALDH1A1 (0.59) | ALDH1A1MAPTHPGDGAAKDM4E | |
| SCHEMBL15921037 | 0.77 | MAPT (0.52) | ALDH1A1MAPTHPGDGAAKDM4E | |
| SCHEMBL2306052 | 0.73 | MAPT (0.80) | ALDH1A1MAPTHPGDGAAKDM4E | |
| SCHEMBL20254477 | 0.72 | PTPN5 (0.53) | ALDH1A1MAPTHPGDGAAAIP | |
| SCHEMBL3987732 | 0.72 | ALDH1A1 (0.78) | ALDH1A1MAPTHPGDGAAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2932981-A2 | Albumin-binding derivatives of GLP-1 | NOVO NORDISK A/S (DK) | 2015-10-21 | — | — | EP | disclosed |