Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | IGF1R | P08069 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 2/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 5/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 5/20 | 0.36 |
| ▸ | HTR2C | P28335 | 4/20 | 0.36 |
| ▸ | DRD1 | P21728 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | NNMT | P40261 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1559298 | 0.88 | ALDH1A1 (0.51) | ALDH1A1TP53CYP1A2HPGDSMN1; SMN2 | |
| SCHEMBL2608535 | 0.76 | GAA (0.43) | ALDH1A1TP53CYP1A2HPGDSMN1; SMN2 | |
| SCHEMBL1769811 | 0.72 | CHRNB2 (0.42) | ALDH1A1TP53CYP1A2HPGDSMN1; SMN2 | |
| SCHEMBL30358032 | 0.71 | ALDH1A1 (0.51) | ALDH1A1TP53CYP1A2HPGDSMN1; SMN2 | |
| SCHEMBL7335768 | 0.71 | ALDH1A1 (0.51) | ALDH1A1TP53CYP1A2HPGDSMN1; SMN2 | |
| SCHEMBL17656944 | 0.70 | DRD2 (0.40) | DRD2DRD3MTNR1AMTNR1BHTR2C | |
| SCHEMBL7433964 | 0.70 | SMYD3 (0.56) | ALDH1A1CYP1A2HPGDHSD17B10IGF1R | |
| SCHEMBL8567081 | 0.70 | SMYD3 (0.56) | ALDH1A1CYP1A2HPGDHSD17B10IGF1R | |
| SCHEMBL926907 | 0.70 | SMYD3 (0.56) | ALDH1A1CYP1A2HPGDHSD17B10IGF1R | |
| SCHEMBL30357995 | 0.70 | SMYD3 (0.56) | ALDH1A1CYP1A2HPGDHSD17B10IGF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110112104-A1 | TRICYCLIC COMPOUNDS, A PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM. | LES LABORATOIRES SERVIER (FR) | 2011-05-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110112104-A1 | TRICYCLIC COMPOUNDS, A PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM. | BAX, CASP3, BCL2 | ALDH1A1 2604/4885TP53 136/4885CYP1A2 34/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.