Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 2/20 | 0.43 |
| ▸ | BCL2 | P10415 | 13/20 | 0.42 |
| ▸ | BCL2L1 | Q07817 | 9/20 | 0.42 |
| ▸ | BAK1 | Q16611 | 6/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.37 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL1769801 | 0.85 | DRD2 (0.41) | HTR7BCL2BCL2L1BAK1DRD2 | |
| SCHEMBL1769700 | 0.84 | ALDH1A1 (0.44) | DRD2 | |
| SCHEMBL1769685 | 0.84 | HTR7 (0.45) | HTR7BCL2BCL2L1BAK1DRD2 | |
| SCHEMBL5128824 | 0.78 | BCL2 (0.44) | HTR7BCL2BCL2L1BAK1DRD2 | |
| Trifluoroacetic Acid SCHEMBL1769915 | 0.78 | F10 (0.38) | BCL2BCL2L1BAK1IDO1 | |
| SCHEMBL5123692 | 0.77 | DRD2 (0.51) | HTR7BCL2BCL2L1BAK1DRD2 | |
| SCHEMBL5126392 | 0.77 | DRD2 (0.51) | HTR7BCL2BCL2L1BAK1DRD2 | |
| Hydrochloric Acid SCHEMBL5132534 | 0.76 | DRD2 (0.50) | HTR7BCL2BCL2L1BAK1DRD2 | |
| SCHEMBL5131792 | 0.74 | HDAC1 (0.42) | HTR7BCL2BCL2L1BAK1DRD2 | |
| SCHEMBL6110571 | 0.74 | DRD2 (0.45) | DRD2CXCR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110112104-A1 | TRICYCLIC COMPOUNDS, A PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM. | LES LABORATOIRES SERVIER (FR) | 2011-05-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110112104-A1 | TRICYCLIC COMPOUNDS, A PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM. | BAX, CASP3, BCL2 | HTR7 261/4885BCL2 3/4885BCL2L1 56/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.