Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.34 |
| ▸ | TACR1 | P25103 | 1/20 | 0.33 |
| ▸ | RBP4 | P02753 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | AGER | Q15109 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | SLC13A5 | Q86YT5 | 2/20 | 0.32 |
| ▸ | CETP | P11597 | 4/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1353016 | 0.75 | TRIM24 (0.41) | KDM4EMAPTPOLBNAPRTL3MBTL1 | |
| SCHEMBL870085 | 0.75 | KDM4E (0.36) | KDM4EMAPTCYP1A2POLBNAPRT | |
| SCHEMBL3398126 | 0.75 | NAPRT (0.39) | KDM4EMAPTCYP1A2POLBNAPRT | |
| SCHEMBL2302256 | 0.74 | KDM4E (0.42) | KDM4EMAPTPOLBNAPRTL3MBTL1 | |
| SCHEMBL17817792 | 0.71 | SMN1; SMN2 (0.44) | KDM4EMAPTCYP1A2L3MBTL1MEN1 | |
| SCHEMBL238763 | 0.69 | SMN1; SMN2 (0.46) | KDM4EMAPTCYP1A2POLBNAPRT | |
| SCHEMBL17700421 | 0.68 | NAPRT (0.38) | KDM4EPOLBNAPRTTACR1ALDH1A1 | |
| SCHEMBL345613 | 0.67 | KDM4E (0.36) | KDM4ENAPRT | |
| SCHEMBL1819971 | 0.66 | POLB (0.55) | KDM4EPOLBNAPRTL3MBTL1MEN1 | |
| SCHEMBL5582871 | 0.66 | KDM4E (0.36) | KDM4EMAPTCYP1A2POLBNAPRT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9776962-B2 | Aromatic compounds with GPR40 agonistic activity | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2017-10-03 | — | — | US | disclosed |
| US-20160115128-A1 | AROMATIC COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2016-04-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160115128-A1 | AROMATIC COMPOUND | GLP1R, GPR119, GPR39 | KDM4E 662/4885MAPT 3476/4885CYP1A2 3765/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.