Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | DHODH | Q02127 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | P2RY1 | P47900 | 4/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | TACR1 | P25103 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.33 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.33 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.33 |
| ▸ | WNT3A | P56704 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3398129 | 0.76 | P2RY1 (0.38) | NAPRTPOLBKDM4EALDH1A1P2RY1 | |
| SCHEMBL17817791 | 0.75 | POLB (0.61) | POLBALDH1A1GAA | |
| SCHEMBL5242161 | 0.74 | P2RY1 (0.39) | POLBKDM4EALDH1A1P2RY1GAA | |
| SCHEMBL14803694 | 0.71 | ALDH1A1 (0.38) | KDM4EALDH1A1P2RY1TACR1TDP1 | |
| SCHEMBL14803892 | 0.69 | KDM4E (0.38) | POLBKDM4EALDH1A1P2RY1TDP1 | |
| SCHEMBL14803583 | 0.68 | SMN1; SMN2 (0.36) | ALDH1A1P2RY1GAATDP1 | |
| SCHEMBL17700417 | 0.68 | KDM4E (0.38) | NAPRTPOLBKDM4EALDH1A1GAA | |
| SCHEMBL30744808 | 0.67 | KDM4E (0.52) | NAPRTDHODHHDAC6KDM4EALDH1A1 | |
| SCHEMBL14803588 | 0.67 | ALDH1A1 (0.34) | KDM4EALDH1A1P2RY1GAATDP1 | |
| SCHEMBL14803703 | 0.67 | HSD17B10 (0.42) | POLBKDM4EALDH1A1TRPV1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9776962-B2 | Aromatic compounds with GPR40 agonistic activity | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2017-10-03 | — | — | US | disclosed |
| US-20160115128-A1 | AROMATIC COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2016-04-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160115128-A1 | AROMATIC COMPOUND | GLP1R, GPR119, GPR39 | NAPRT 3677/4885POLB 4857/4885OPRM1 2606/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.