SCHEMBL17705394

SCHEMBL17705394

O=C(O)c1ccc(/C=C/c2ccc(N(c3ccccc3)c3ccccc3)cc2)s1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.41
APP P05067 3/20 0.40
CTDSP1 Q9GZU7 1/20 0.40
MAPT P10636 1/20 0.38
RELA Q04206 1/20 0.38
MEN1 O00255 2/20 0.37
POLB P06746 2/20 0.37
KMT2A Q03164 2/20 0.37
PSMD14 O00487 1/20 0.37
APAF1 O14727 1/20 0.37
USP2 O75604 1/20 0.37
MMP2 P08253 1/20 0.37
RAD52 P43351 1/20 0.37
CASP6 P55212 1/20 0.37
UBE2N P61088 1/20 0.37
TRPM8 Q7Z2W7 2/20 0.37
RAB9A P51151 1/20 0.37
HDAC3 O15379 1/20 0.37
HDAC1 Q13547 1/20 0.37
HDAC2 Q92769 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8437696 0.86 ALOX5 (0.48) ALOX5MAPTMEN1POLBKMT2A
SCHEMBL8435188 0.86 ALOX5 (0.48) ALOX5MAPTMEN1POLBKMT2A
SCHEMBL8435184 0.86 ALOX5 (0.48) ALOX5MAPTMEN1POLBKMT2A
SCHEMBL13206646 0.84 RELA (0.50) APPMAPTRELAMEN1KMT2A
SCHEMBL34474392 0.80 APP (0.57) ALOX5APPCTDSP1MAPTRELA
SCHEMBL22380001 0.79 DAO (0.52) MEN1POLBKMT2ARAB9AHDAC3
SCHEMBL10144497 0.77 L3MBTL1 (0.40) ALOX5APPCTDSP1RELAMEN1
SCHEMBL14856712 0.76 HDAC1 (0.50) CTDSP1MAPTRELAMEN1KMT2A
SCHEMBL19285487 0.75 MAPT (0.66) APPMAPTKMT2A
SCHEMBL12327596 0.75 MAPT (0.66) APPMAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9812263-B2 Compound and photoelectric conversion device ADEKA CORPORATION (JP) 2017-11-07 US disclosed
US-9812263-B2 Compound and photoelectric conversion device ADEKA CORPORATION (JP) 2017-11-07 US disclosed
US-20160211085-A1 NOVEL COMPOUND AND PHOTOELECTRIC CONVERSION DEVICE ADEKA CORPORATION (JP) 2016-07-21 US disclosed
US-20160211085-A1 NOVEL COMPOUND AND PHOTOELECTRIC CONVERSION DEVICE ADEKA CORPORATION (JP) 2016-07-21 US disclosed
US-9324889-B2 Compound and photoelectric conversion device ADEKA CORPORATION (JP) 2016-04-26 US disclosed
US-9324889-B2 Compound and photoelectric conversion device ADEKA CORPORATION (JP) 2016-04-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160211085-A1 NOVEL COMPOUND AND PHOTOELECTRIC CONVERSION DEVICE CYP1B1, PAH, CRY1 ALOX5 1645/4885APP 1249/4885CTDSP1 3272/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.