Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.67 |
| ▸ | MEN1 | O00255 | 3/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.67 |
| ▸ | LMNA | P02545 | 1/20 | 0.67 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.67 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | PDK2 | Q15119 | 3/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15782771 | 0.88 | MEN1 (0.49) | MAPTMEN1KMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL29128950 | 0.82 | MAPT (0.79) | MAPTMEN1KMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL29392989 | 0.82 | MAPT (1.00) | MAPTMEN1KMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL105428 | 0.82 | MAPT (1.00) | MAPTMEN1KMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL29426418 | 0.82 | MAPT (1.00) | MAPTMEN1KMT2AKDM4ESMN1; SMN2 | |
| Ammonia Solution, Strong SCHEMBL2046821 | 0.80 | MEN1 (0.96) | MAPTMEN1KMT2AKDM4ESMN1; SMN2 | |
| Ammonia Solution, Strong SCHEMBL7052845 | 0.80 | MEN1 (0.96) | MAPTMEN1KMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL7050425 | 0.80 | MAPT (0.73) | MAPTMEN1KMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL17819277 | 0.78 | MAPT (0.92) | MAPTMEN1KMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL31537252 | 0.78 | MAPT (0.92) | MAPTMEN1KMT2AKDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160114042-A1 | AMINE-CONTAINING LIPIDOIDS AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2016-04-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160114042-A1 | AMINE-CONTAINING LIPIDOIDS AND USES THEREOF | ABCB4, PHOSPHO1, SGMS2 | MAPT 3385/4885MEN1 2774/4885KMT2A 267/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.