SCHEMBL177101

SCHEMBL177101

Nc1cccc(C(=O)O)c1Cl

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.63
MMP2 P08253 1/20 0.61
CYP3A4 P08684 1/20 0.53
ALDH1A1 P00352 4/20 0.50
G6PD P11413 1/20 0.50
CASP7 P55210 1/20 0.50
CASP6 P55212 1/20 0.50
ALOX15 P16050 1/20 0.48
POLB P06746 1/20 0.46
CDC25B P30305 1/20 0.46
MAPT P10636 2/20 0.45
GAA P10253 1/20 0.45
P2RX7 Q99572 1/20 0.44
SMN1; SMN2 Q16637 2/20 0.44
NAPRT Q6XQN6 2/20 0.44
IDO1 P14902 1/20 0.44
LMNA P02545 1/20 0.44
KDM4E B2RXH2 3/20 0.44
NPC1 O15118 1/20 0.44
CASP3 P42574 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL11176877 0.98 TSHR (0.61) TSHRMMP2CYP3A4ALDH1A1G6PD
SCHEMBL10434372 0.91 TSHR (0.53) TSHRMMP2CYP3A4ALDH1A1G6PD
SCHEMBL1614730 0.84 TSHR (0.77) TSHRMMP2ALDH1A1G6PDCASP7
SCHEMBL19972058 0.83 P2RX7 (0.48) TSHRMMP2CYP3A4ALDH1A1G6PD
SCHEMBL14661611 0.83 MMP2 (0.45) TSHRMMP2CYP3A4ALDH1A1MAPT
Hydrochloric Acid SCHEMBL21808814 0.81 TSHR (0.74) TSHRMMP2ALDH1A1G6PDCASP7
Hydrochloric Acid SCHEMBL11483376 0.81 TSHR (0.74) TSHRMMP2ALDH1A1G6PDCASP7
SCHEMBL5363326 0.81 MMP2 (0.44) TSHRMMP2CYP3A4ALDH1A1POLB
SCHEMBL10618808 0.80 MAPT (0.69) MMP2ALDH1A1ALOX15POLBMAPT
SCHEMBL7375794 0.80 CYP3A4 (0.50) TSHRMMP2CYP3A4ALDH1A1CASP6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 338 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1284773-C Ortho-pyridinequinone derivative, composite containing said derivative, its preparation method and application BAIRUI GLOBAL CO LTD (VG) 2006-11-15 CN claimed
CN-1477099-A O-pyridinoquinone derivative, composition containing the same, preparation method and use of the same 百瑞全球有限公司 2004-02-25 CN claimed
JP-9286766-A None JP disclosed
US-20250288872-A1 MULTI-COLOR URETHANE GOLF BALL TAYLOR MADE GOLF COMPANY, INC. (US) 2025-09-18 US disclosed
US-20250242208-A1 GOLF BALL WITH SOFTER FEEL AND HIGHER IRON SPIN TAYLOR MADE GOLF COMPANY, INC. (US) 2025-07-31 US disclosed
US-20250144477-A1 GOLF BALL TAYLOR MADE GOLF COMPANY, INC. (US) 2025-05-08 US disclosed
US-12233314-B2 Golf ball TAYLOR MADE GOLF COMPANY, INC. (US) 2025-02-25 US disclosed
WO-2025036384-A1 METHOD FOR PREPARING 2-CHLORO-3-AMINOBENZOIC ACID AND ESTER COMPOUND THEREOF 沈阳中化农药化工研发有限公司 2025-02-20 WO disclosed
EP-3498693-B1 HETEROCYCLIC COMPOUND TAKEDA PHARMACEUTICALS CO (JP) 2024-10-30 EP disclosed
WO-2024130161-A2 NOVEL CAMPTOTHECIN DERIVATIVES AND CONJUGATES THEREOF BIONECURE THERAPEUTICS INC (US) 2024-06-20 WO disclosed
US-11975241-B2 Golf ball TAYLOR MADE GOLF COMPANY, INC. (US) 2024-05-07 US disclosed
EP-0595082-A2 Thermoplastically processable thermotropic moulding composition BAYER AG (DE) 1994-05-04 EP disclosed
CN-1081815-A Safe with pyrazolyl sulfonylureas of activity of weeding MONSANTO CO (US) 1994-02-16 CN disclosed
CN-1063015-A Safe herbicidal sulfonamide compositions MONSANTO CO (US) 1992-07-29 CN disclosed
CN-1062263-A The weed killer herbicide that contains the pyridinsulfonamide compounds of replacement ISHIHARA SANGYO KAISHA (JP) 1992-07-01 CN disclosed
CN-1016661-B Herbicidal composition containing pyridine sulfonamide ISHIHARA SANGYO KAISHA (JP) 1992-05-20 CN disclosed
US-5075361-A Solubilizers TEXACO INC. (US) 1991-12-24 US disclosed
CN-1052768-A The safe handling of imidazolidinone weedicide MONSANTO CO (US) 1991-07-10 CN disclosed
CN-1039949-A The protection of benzoic acid derivative class weed killer herbicide MONSANTO CO (US) 1990-02-28 CN disclosed
US-4104049-A Chlorine-substituted vinylaminobenzoic acid compounds and plant growth regulant compositions BAYER AKTIENGESELLSCHAFT (DE) 1978-08-01 US disclosed