Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1B | P49286 | 8/20 | 0.52 |
| ▸ | MTNR1A | P48039 | 8/20 | 0.52 |
| ▸ | XIAP | P98170 | 1/20 | 0.46 |
| ▸ | REN | P00797 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 2/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | ACACB | O00763 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1770990 | 0.97 | MTNR1A (0.53) | MTNR1BMTNR1AXIAPRENCYP3A4 | |
| SCHEMBL1770499 | 0.95 | MTNR1A (0.50) | MTNR1BMTNR1AXIAPRENCYP3A4 | |
| SCHEMBL1770917 | 0.90 | XIAP (0.47) | MTNR1BMTNR1AXIAPMAOBMAOA | |
| SCHEMBL1770647 | 0.89 | HPGD (0.46) | MTNR1BMTNR1AXIAP | |
| SCHEMBL27794657 | 0.88 | XIAP (0.45) | XIAPMAOBMAOA | |
| SCHEMBL1770407 | 0.87 | XIAP (0.46) | MTNR1BMTNR1AXIAPCYP3A4 | |
| SCHEMBL1770507 | 0.87 | MAOA (0.44) | MTNR1BMTNR1AXIAPMAOBMAOA | |
| SCHEMBL1770327 | 0.85 | MTNR1A (0.47) | MTNR1BMTNR1AXIAP | |
| SCHEMBL6728768 | 0.83 | TRPV1 (0.49) | MTNR1BMTNR1ARENCYP3A4L3MBTL1 | |
| SCHEMBL27794658 | 0.82 | XIAP (0.43) | XIAPMAOBMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110112148-A1 | INDOLINE COMPOUNDS | FERRER INTERNACIONAL S.A. | 2011-05-12 | — | — | US | claimed |
| CN-101878200-A | Indoline compound | FERRER INT | 2010-11-03 | — | — | CN | claimed |
| EP-2203423-A1 | INDOLINE COMPOUNDS | Ferrer Internacional, S.A. (ES) | 2010-07-07 | — | — | EP | claimed |
| WO-2009053440-A1 | INDOLINE COMPOUNDS | FERRER INTERNACIONAL S.A. (ES) | 2009-04-30 | — | — | WO | claimed |
| US-20110112148-A1 | INDOLINE COMPOUNDS | FERRER INTERNACIONAL S.A. | 2011-05-12 | — | — | US | disclosed |
| CN-101878200-A | Indoline compound | FERRER INT | 2010-11-03 | — | — | CN | disclosed |
| EP-2203423-A1 | INDOLINE COMPOUNDS | Ferrer Internacional, S.A. (ES) | 2010-07-07 | — | — | EP | disclosed |
| WO-2009053440-A1 | INDOLINE COMPOUNDS | FERRER INTERNACIONAL S.A. (ES) | 2009-04-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110112148-A1 | INDOLINE COMPOUNDS | MTNR1A, MTNR1B, TPH2 | MTNR1B 2/4885MTNR1A 1/4885XIAP 1156/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.