SCHEMBL17712318

SCHEMBL17712318

CCC(CC)COC(=O)C(C)N[P@](=O)(Oc1ccccc1)Oc1ccc([N+](=O)[O-])cc1

nearest known ligand 0.47

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 3/20 0.47
▸ CA1 P00915 2/20 0.43
▸ CA2 P00918 2/20 0.43
▸ BCHE P06276 1/20 0.43
▸ ACHE P22303 1/20 0.43
▸ MEN1 O00255 3/20 0.41
▸ KMT2A Q03164 3/20 0.41
▸ CES2 O00748 1/20 0.41
▸ CES1 P23141 1/20 0.41
▸ NPSR1 Q6W5P4 1/20 0.41
▸ BTN3A1 O00481 4/20 0.40
▸ MAPT P10636 1/20 0.40
▸ NPC1 O15118 1/20 0.40
▸ TP53 P04637 1/20 0.40
▸ RAB9A P51151 1/20 0.40
▸ SMN1; SMN2 Q16637 1/20 0.40
▸ CYP2C9 P11712 1/20 0.40
▸ CYP2C19 P33261 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17712317 1.00 ALDH1A1 (0.47) ALDH1A1CA1CA2BCHEACHE
SCHEMBL28854869 1.00 ALDH1A1 (0.47) ALDH1A1CA1CA2BCHEACHE
SCHEMBL14989469 1.00 ALDH1A1 (0.47) ALDH1A1CA1CA2BCHEACHE
SCHEMBL28645682 1.00 ALDH1A1 (0.47) ALDH1A1CA1CA2BCHEACHE
SCHEMBL14989468 1.00 ALDH1A1 (0.47) ALDH1A1CA1CA2BCHEACHE
SCHEMBL16554025 0.97 CA1 (0.45) ALDH1A1CA1CA2BCHEACHE
SCHEMBL16554022 0.97 CA1 (0.45) ALDH1A1CA1CA2BCHEACHE
SCHEMBL16566219 0.92 ALDH1A1 (0.43) ALDH1A1CA1CA2BCHEACHE
SCHEMBL23819216 0.91 BTN3A1 (0.44) ALDH1A1CA1CA2BCHEACHE
SCHEMBL13469579 0.90 ALDH1A1 (0.47) ALDH1A1CA1CA2BCHEACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113493480-A Preparation and analysis method of Reidesciclovir isomer 南京正大天晴制药有限公司 2021-10-12 — — CN claimed
EP-4591935-A2 METHODS FOR THE PREPARATION OF RIBOSIDES Gilead Sciences, Inc. (US) 2025-07-30 — — EP disclosed
EP-4588928-A2 METHODS FOR TREATING FILOVIRIDAE VIRUS INFECTIONS Gilead Sciences, Inc. (US) 2025-07-23 — — EP disclosed
EP-4036099-B1 METHODS FOR THE PREPARATION OF RIBOSIDES GILEAD SCIENCES INC (US) 2025-03-19 — — EP disclosed
CN-115403626-A Novel crystalline forms 吉利德科学公司 2022-11-29 — — CN disclosed
US-20220354873-A1 METHODS FOR THE PREPARATION OF RIBOSIDES GILEAD SCIENCES, INC. 2022-11-10 — — US disclosed
CN-110636884-B Novel crystalline forms 吉利德科学公司 2022-10-04 — — CN disclosed
EP-4036099-A1 METHODS FOR THE PREPARATION OF RIBOSIDES Gilead Sciences, Inc. (US) 2022-08-03 — — EP disclosed
US-11344565-B2 Methods for the preparation of ribosides GILEAD SCIENCES, INC. (US) 2022-05-31 — — US disclosed
CN-114191438-A Methods of treating filoviridae virus infections 吉利德科学公司 2022-03-18 — — CN disclosed
US-9949994-B2 Methods for treating Filoviridae virus infections GILEAD SCIENCES, INC. (US) 2018-04-24 — — US disclosed
EP-3212175-A1 METHODS FOR THE PREPARATION OF RIBOSIDES Gilead Sciences, Inc. (US) 2017-09-06 — — EP disclosed
EP-3212174-A1 METHODS FOR TREATING FILOVIRIDAE VIRUS INFECTIONS Gilead Sciences, Inc. (US) 2017-09-06 — — EP disclosed
US-9724360-B2 Methods for treating Filoviridae virus infections GILEAD SCIENCES, INC. (US) 2017-08-08 — — US disclosed
US-20160361330-A1 METHODS FOR TREATING FILOVIRIDAE VIRUS INFECTIONS GILEAD SCIENCES, INC. 2016-12-15 — — US disclosed
WO-2016069827-A1 METHODS FOR TREATING FILOVIRIDAE VIRUS INFECTIONS GILEAD SCIENCES, INC. (US) 2016-05-06 — — WO disclosed
WO-2016069825-A1 METHODS FOR THE PREPARATION OF RIBOSIDES GILEAD SCIENCES, INC. (US) 2016-05-06 — — WO disclosed
WO-2016069826-A1 METHODS FOR TREATING FILOVIRIDAE VIRUS INFECTIONS GILEAD SCIENCES, INC. (US) 2016-05-06 — — WO disclosed
US-20160122356-A1 METHODS FOR THE PREPARATION OF RIBOSIDES GILEAD SCIENCES, INC. 2016-05-05 — — US disclosed
US-20160122374-A1 METHODS FOR TREATING FILOVIRIDAE VIRUS INFECTIONS GILEAD SCIENCES, INC. 2016-05-05 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160122356-A1 METHODS FOR THE PREPARATION OF RIBOSIDES PRPS1, PRPF4, PRPF31 ALDH1A1 1567/4885CA1 4736/4885CA2 4682/4885
US-20160361330-A1 METHODS FOR TREATING FILOVIRIDAE VIRUS INFECTIONS PNP, PRPF4, RPIA ALDH1A1 1121/4885CA1 4046/4885CA2 3661/4885
US-20220354873-A1 METHODS FOR THE PREPARATION OF RIBOSIDES PRPS1, PRPF4, PRPF31 ALDH1A1 1567/4885CA1 4736/4885CA2 4682/4885
US-11344565-B2 Methods for the preparation of ribosides RUVBL2, RUVBL1, EIF2AK2 ALDH1A1 4115/4885CA1 3198/4885CA2 1859/4885
US-20160122374-A1 METHODS FOR TREATING FILOVIRIDAE VIRUS INFECTIONS PNP, PRPF4, RPIA ALDH1A1 1121/4885CA1 4046/4885CA2 3661/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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