Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.41 |
| ▸ | CPB2 | Q96IY4 | 14/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5261062 | 0.72 | SLC1A3 (0.51) | FOLH1CPB2CA1CA2 | |
| SCHEMBL5261067 | 0.72 | SLC1A3 (0.51) | FOLH1CPB2CA1CA2 | |
| SCHEMBL28456990 | 0.70 | FOLH1 (0.60) | FOLH1CPB2CA1CA2 | |
| SCHEMBL17714030 | 0.70 | FOLH1 (0.41) | FOLH1CPB2 | |
| SCHEMBL28263995 | 0.70 | HDAC4 (0.52) | FOLH1CPB2 | |
| SCHEMBL454654 | 0.70 | HDAC4 (0.52) | FOLH1CPB2 | |
| SCHEMBL25409269 | 0.69 | TGM2 (0.47) | FOLH1CA1CA2 | |
| SCHEMBL9698704 | 0.69 | FOLH1 (0.58) | FOLH1CPB2CA1CA2 | |
| SCHEMBL3435138 | 0.69 | FOLH1 (0.58) | FOLH1CPB2CA1CA2 | |
| SCHEMBL19689232 | 0.69 | FOLH1 (0.43) | FOLH1CPB2CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107002088-B | Incorporation of unnatural amino acids into proteins | 英国研究与创新署 | 2022-01-11 | — | — | CN | disclosed |
| US-10738339-B2 | Use of eRF1 mutants in unnatural amino acid incorporation | UNITED KINGDOM RESEARCH AND INNOVATION (GB) | 2020-08-11 | — | — | US | disclosed |
| EP-3212799-B1 | INCORPORATION OF UNNATURAL AMINO ACIDS INTO PROTEINS | RES & INNOVATION UK (GB) | 2019-04-17 | — | — | EP | disclosed |
| US-20170356023-A1 | USE OF eRF1 MUTANTS IN UNNATURAL AMINO ACID INCORPORATION | UNITED KINGDOM RESEARCH AND INNOVATION (GB) | 2017-12-14 | — | — | US | disclosed |
| EP-3212799-A1 | INCORPORATION OF UNNATURAL AMINO ACIDS INTO PROTEINS | Medical Research Council (GB) | 2017-09-06 | — | — | EP | disclosed |
| WO-2016066995-A1 | INCORPORATION OF UNNATURAL AMINO ACIDS INTO PROTEINS | MEDICAL RESEARCH COUNCIL (GB) | 2016-05-06 | — | — | WO | disclosed |