SCHEMBL454654

SCHEMBL454654

NCCCC[C@H](NC(=O)OC1CCCC1)C(=O)O

nearest known ligand 0.52

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
HDAC4 P56524 1/20 0.52
HDAC1 Q13547 1/20 0.52
CPB2 Q96IY4 15/20 0.50
FOLH1 Q04609 1/20 0.49
EPHX1 P07099 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28263995 1.00 HDAC4 (0.52) HDAC4HDAC1CPB2FOLH1EPHX1
SCHEMBL16915092 0.90 HDAC4 (0.44) HDAC4HDAC1CPB2FOLH1
SCHEMBL16915094 0.90 HDAC4 (0.44) HDAC4HDAC1CPB2FOLH1
SCHEMBL16915024 0.88 CPB2 (0.43) HDAC4HDAC1CPB2FOLH1
SCHEMBL16915025 0.88 CPB2 (0.43) HDAC4HDAC1CPB2FOLH1
SCHEMBL2805502 0.85 HDAC4 (0.52) HDAC4HDAC1CPB2EPHX1
SCHEMBL2805504 0.85 HDAC4 (0.52) HDAC4HDAC1CPB2EPHX1
SCHEMBL27780890 0.84 HDAC4 (0.54) HDAC4HDAC1EPHX1
SCHEMBL22777304 0.84 EPHX1 (0.51) HDAC4HDAC1EPHX1
Hydrochloric Acid SCHEMBL4446986 0.83 HDAC4 (0.53) HDAC4HDAC1EPHX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 136 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4526336-A1 NOVEL RECOMBINANT FIBRINOGEN VARIANTS FOR FIBRIN SEALANTS FOR SURGICAL WOUND CARE Julius-Maximilians-Universität Würzburg (DE) 2025-03-26 EP claimed
CN-118256603-A Modified enzymes 牛津纳米孔科技公开有限公司 2024-06-28 CN claimed
WO-2023222770-A1 Novel recombinant fibrinogen variants for fibrin sealants for surgical wound care JULIUS-MAXIMILIANS-UNIVERSITAET WUERZBURG (DE) 2023-11-23 WO claimed
US-20230212535-A1 MODIFIED HELICASES OXFORD NANOPORE TECHNOLOGIES PLC (GB) 2023-07-06 US claimed
EP-4198125-A2 PIF1-LIKE HELICASE AND USE THEREOF Qitan Technology Ltd., Beijing (CN) 2023-06-21 EP claimed
US-11525125-B2 Modified helicases OXFORD NANOPORE TECHNOLOGIES PLC (GB) 2022-12-13 US claimed
EP-4063382-A9 PIF1-LIKE HELICASE AND APPLICATION THEREOF Qitan Technology Ltd., Beijing (CN) 2022-11-16 EP claimed
US-20210009971-A1 MODIFIED HELICASES OXFORD NANOPORE TECHNOLOGIES LTD. (GB) 2021-01-14 US claimed
EP-3575410-A2 MODIFIED ENZYMES Oxford Nanopore Technologies Limited (GB) 2019-12-04 EP claimed
US-20180037874-A9 MODIFIED HELICASES OXFORD NANOPORE TECHNOLOGIES LTD. (GB) 2018-02-08 US claimed
US-20160257942-A1 MODIFIED HELICASES OXFORD NANOPORE TECHNOLOGIES LTD. (GB) 2016-09-08 US claimed
EP-3058088-A2 MODIFIED ENZYMES Oxford Nanopore Technologies Limited (GB) 2016-08-24 EP claimed
US-20150191709-A1 MODIFIED HELICASES OXFORD NANOPORE TECHNOLOGIES LIMITED (GB) 2015-07-09 US claimed
EP-2875128-A1 MODIFIED HELICASES Oxford Nanopore Technologies Limited (GB) 2015-05-27 EP claimed
WO-2015055981-A2 MODIFIED ENZYMES OXFORD NANOPORE TECHNOLOGIES LIMITED (GB) 2015-04-23 WO claimed
WO-2014013260-A1 MODIFIED HELICASES OXFORD NANOPORE TECHNOLOGIES LIMITED (GB) 2014-01-23 WO claimed
US-20260001937-A1 NOVEL RECOMBINANT FIBRINOGEN VARIANTS FOR FIBRIN SEALANTS FOR SURGICAL WOUND CARE JULIUS-MAXIMILIANS-UNIVERSITÄT WÜRZBURG (DE) 2026-01-01 US disclosed
US-20250388669-A1 MULTI-SPECIFIC ANTIBODIES IN USES THEREOF IN AVIDITY RECEPTOR CROSSLINKING AND IMMUNE MODULATION Wang, Jieyi (US) 2025-12-25 US disclosed
EP-2212422-A1 METHODS AND COMPOSITIONS Medical Research Council (GB) 2010-08-04 EP disclosed
WO-2009056803-A1 METHODS AND COMPOSITIONS MEDICAL RESEARCH COUNCIL (GB) 2009-05-07 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250388669-A1 MULTI-SPECIFIC ANTIBODIES IN USES THEREOF IN AVIDITY RECEPTOR CROSSLINKING AND IMMUNE MODULATION TNFRSF9, FCGR3B, FCGR2A HDAC4 3653/4885HDAC1 3518/4885CPB2 3275/4885
US-20260001937-A1 NOVEL RECOMBINANT FIBRINOGEN VARIANTS FOR FIBRIN SEALANTS FOR SURGICAL WOUND CARE FGB, F7, F11 HDAC4 4772/4885HDAC1 4209/4885CPB2 759/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.