SCHEMBL17714867

SCHEMBL17714867

CC1(C)OB(c2cc(C#N)cc(-c3nc(-c4ccccc4)nc(-c4ccccc4)n3)c2)OC1(C)C

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ LPL P06858 2/20 0.47
▸ LIPG Q9Y5X9 2/20 0.47
▸ MEN1 O00255 4/20 0.40
▸ KMT2A Q03164 4/20 0.40
▸ ALDH1A1 P00352 3/20 0.40
▸ CYP1A2 P05177 3/20 0.40
▸ CYP3A4 P08684 2/20 0.40
▸ CYP2C19 P33261 2/20 0.40
▸ CLK4 Q9HAZ1 2/20 0.40
▸ LMNA P02545 2/20 0.40
▸ TSHR P16473 2/20 0.40
▸ HSD17B10 Q99714 2/20 0.40
▸ CYP2D6 P10635 1/20 0.40
▸ CYP2C9 P11712 1/20 0.40
▸ ABCG2 Q9UNQ0 11/20 0.39
▸ ABCB1 P08183 6/20 0.39
▸ MAPK1 P28482 1/20 0.38
▸ GRM5 P41594 1/20 0.36
▸ ABCC1 P33527 3/20 0.36
▸ DGAT1 O75907 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL32682796 1.00 LPL (0.47) LPLLIPGMEN1KMT2AALDH1A1
SCHEMBL25709623 0.89 LIPG (0.57) LPLLIPGMEN1KMT2AALDH1A1
SCHEMBL21628353 0.88 LIPG (0.57) LPLLIPGTSHRDGAT1
SCHEMBL23383842 0.88 CYP1A2 (0.49) LPLLIPGMEN1KMT2AALDH1A1
SCHEMBL25709653 0.87 LPL (0.42) LPLLIPGMEN1KMT2AALDH1A1
SCHEMBL18419165 0.86 LIPG (0.57) LPLLIPGMEN1KMT2AALDH1A1
SCHEMBL2363798 0.86 LIPG (0.57) LPLLIPGMEN1KMT2AALDH1A1
SCHEMBL23383917 0.85 LIPG (0.49) LPLLIPGMEN1KMT2AALDH1A1
SCHEMBL23383843 0.85 LIPG (0.55) LPLLIPGMEN1KMT2AALDH1A1
SCHEMBL23383914 0.85 LIPG (0.48) LPLLIPGMEN1KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240023355-A1 ORGANIC LIGHT EMITTING DEVICE LG CHEM, LTD. (KR) 2024-01-18 — — US disclosed
US-20240023355-A1 ORGANIC LIGHT EMITTING DEVICE LG CHEM, LTD. (KR) 2024-01-18 — — US disclosed
US-11800730-B2 Organic light emitting device LG CHEM, LTD. (KR) 2023-10-24 — — US disclosed
US-11800730-B2 Organic light emitting device LG CHEM, LTD. (KR) 2023-10-24 — — US disclosed
US-11685859-B2 Organic light emitting device LG CHEM, LTD. (KR) 2023-06-27 — — US disclosed
US-11685859-B2 Organic light emitting device LG CHEM, LTD. (KR) 2023-06-27 — — US disclosed
US-11111231-B2 Heterocyclic compound and organic light-emitting device comprising same LG CHEM, LTD. (KR) 2021-09-07 — — US disclosed
US-20210151688-A1 COMPOUND FOR ORGANIC OPTOELECTRONIC DEVICE, COMPOSITION FOR ORGANIC OPTOELECTRONIC DEVICE, ORGANIC OPTOELECTRONIC DEVICE AND DISPLAY DEVICE SAMSUNG SDI CO., LTD. (KR) 2021-05-20 — — US disclosed
US-20210009894-A1 ORGANIC LIGHT EMITTING DEVICE LG CHEM, LTD. (KR) 2021-01-14 — — US disclosed
EP-3015465-B1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME LG CHEMICAL LTD (KR) 2019-09-04 — — EP disclosed
US-20190127352-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME LG CHEM, LTD. (KR) 2019-05-02 — — US disclosed
US-10253016-B2 Heterocyclic compound and organic light-emitting device comprising same LG CHEM, LTD. (KR) 2019-04-09 — — US disclosed
US-20160204359-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME LG CHEM, LTD. (KR) 2016-07-14 — — US disclosed
EP-3015465-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME LG Chem, Ltd. (KR) 2016-05-04 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10253016-B2 Heterocyclic compound and organic light-emitting device comprising same CRY1, CRY2, NR2E3 LPL 1334/4885LIPG 2588/4885MEN1 799/4885
US-20160204359-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME CRY1, CRY2, NR2E3 LPL 1334/4885LIPG 2588/4885MEN1 799/4885
US-20240023355-A1 ORGANIC LIGHT EMITTING DEVICE CRY1, CRY2, CYP1A1 LPL 1990/4885LIPG 3161/4885MEN1 699/4885
US-11111231-B2 Heterocyclic compound and organic light-emitting device comprising same CRY1, CRY2, NR2E3 LPL 1334/4885LIPG 2588/4885MEN1 799/4885
US-20190127352-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME CRY1, CRY2, NR2E3 LPL 1334/4885LIPG 2588/4885MEN1 799/4885
US-11800730-B2 Organic light emitting device CRY1, CRY2, MAP1LC3C LPL 543/4885LIPG 987/4885MEN1 2347/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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