Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | CECR2 | Q9BXF3 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | ERN1 | O75460 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16602018 | 0.68 | ALDH1A1 (0.36) | BRD4KDM4EALDH1A1HPGDMEN1 | |
| SCHEMBL16601754 | 0.68 | PTGS2 (0.42) | BRD4ALDH1A1HPGDHDAC2MEN1 | |
| SCHEMBL16601994 | 0.68 | MCL1 (0.49) | BRD4HDAC2 | |
| SCHEMBL4623255 | 0.67 | EGFR (0.48) | EGFRALDH1A1HDAC2SMN1; SMN2 | |
| SCHEMBL17715437 | 0.65 | NPC1 (0.47) | EGFRKDM4EALDH1A1HPGDMEN1 | |
| SCHEMBL92935 | 0.65 | LPL (0.52) | EGFRALDH1A1SMN1; SMN2 | |
| SCHEMBL16807145 | 0.64 | EGFR (0.41) | EGFRALDH1A1ERN1NPC1LMNA | |
| SCHEMBL16807079 | 0.62 | EGFR (0.42) | EGFRALDH1A1NPC1LMNAMAPT | |
| SCHEMBL16807109 | 0.61 | EGFR (0.41) | EGFRALDH1A1NPC1LMNAMAPT | |
| Methylamine SCHEMBL27945331 | 0.61 | TAAR1 (0.50) | ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2680079-B1 | Electrophotographic photosensitive member, process catridge, and electrophotographic apparatus | CANON KK (JP) | 2016-05-04 | — | — | EP | disclosed |