Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A5 | Q9Y345 | 2/20 | 0.54 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.49 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.49 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.49 |
| ▸ | PAOX | Q6QHF9 | 2/20 | 0.46 |
| ▸ | NMT2 | O60551 | 1/20 | 0.44 |
| ▸ | NMT1 | P30419 | 1/20 | 0.44 |
| ▸ | KDM4A | O75164 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.44 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.44 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.42 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CASP2 | P42575 | 1/20 | 0.41 |
| ▸ | RRM1 | P23921 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29300380 | 0.86 | SLC6A5 (0.57) | SLC6A5GNAI3GNAO1GNAI1PAOX | |
| SCHEMBL17740189 | 0.84 | SLC6A5 (0.55) | SLC6A5GNAI3GNAO1GNAI1PAOX | |
| SCHEMBL25962258 | 0.82 | GNAI3 (0.56) | SLC6A5GNAI3GNAO1GNAI1PAOX | |
| SCHEMBL12037630 | 0.82 | SLC6A5 (0.54) | SLC6A5GNAI3GNAO1GNAI1PAOX | |
| SCHEMBL7215984 | 0.82 | SLC6A5 (0.67) | SLC6A5PAOXKDM4AHIF1ATET2 | |
| SCHEMBL7203302 | 0.82 | SLC6A5 (0.67) | SLC6A5PAOXKDM4AHIF1ATET2 | |
| SCHEMBL7209833 | 0.82 | SLC6A5 (0.67) | SLC6A5PAOXKDM4AHIF1ATET2 | |
| SCHEMBL12863577 | 0.82 | SLC6A5 (0.67) | SLC6A5PAOXKDM4AHIF1ATET2 | |
| SCHEMBL7208464 | 0.82 | SLC6A5 (0.67) | SLC6A5PAOXKDM4AHIF1ATET2 | |
| SCHEMBL17373920 | 0.82 | SLC6A5 (0.67) | SLC6A5PAOXKDM4AHIF1ATET2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160122386-A1 | V1A RECEPTOR AGONISTS | OCELOT BIO, INC. | 2016-05-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160122386-A1 | V1A RECEPTOR AGONISTS | AVPR2, AVPR1A, AVPR1B | SLC6A5 1811/4885GNAI3 882/4885GNAO1 564/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.