Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A5 | Q9Y345 | 2/20 | 0.54 |
| ▸ | PAOX | Q6QHF9 | 4/20 | 0.50 |
| ▸ | KDM4A | O75164 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.47 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.47 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.46 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.46 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.46 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.45 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.45 |
| ▸ | NMT2 | O60551 | 1/20 | 0.44 |
| ▸ | NMT1 | P30419 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | CASP2 | P42575 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 2/20 | 0.41 |
| ▸ | NAAA | Q02083 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12391838 | 0.86 | CASP2 (0.42) | SLC6A5CASP2FAAHNAAA | |
| SCHEMBL21563328 | 0.86 | CASP2 (0.59) | SLC6A5CASP2FAAHNAAA | |
| SCHEMBL29300380 | 0.86 | SLC6A5 (0.57) | SLC6A5PAOXKDM4AHIF1ATET2 | |
| SCHEMBL25962258 | 0.85 | GNAI3 (0.56) | SLC6A5PAOXKDM4AHIF1ATET2 | |
| SCHEMBL17740189 | 0.84 | SLC6A5 (0.55) | SLC6A5PAOXKDM4AHIF1ATET2 | |
| SCHEMBL12391833 | 0.83 | ALB (0.40) | SLC6A5LMNACASP2FAAHNAAA | |
| SCHEMBL17718467 | 0.82 | SLC6A5 (0.54) | SLC6A5PAOXKDM4AHIF1ATET2 | |
| SCHEMBL12863577 | 0.82 | SLC6A5 (0.67) | SLC6A5PAOXKDM4AHIF1ATET2 | |
| SCHEMBL7215946 | 0.82 | SLC6A5 (0.67) | SLC6A5PAOXKDM4AHIF1ATET2 | |
| SCHEMBL7203302 | 0.82 | SLC6A5 (0.67) | SLC6A5PAOXKDM4AHIF1ATET2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8357375-B2 | Process for the preparation and use of a bivalent vaccine against morphine-heroine addiction | INSTITUTO NACIONAL DE PSIQUIATRIA RAMON DE LA FUENTE MUNIZ (MX) | 2013-01-22 | — | — | US | disclosed |
| US-20110318381-A1 | PROCESS FOR THE PREPARATION AND USE OF A BIVALENT VACCINE AGAINST MORPHINE-HEROINE ADDICTION | INSTITUTO NACIONAL DE PSIQUIATRIA RAMON DE LA FUENTE MUNIZ (MX) | 2011-12-29 | — | — | US | disclosed |
| US-20080241183-A1 | Process For The Preparation And Use Of A Bivalent Vaccine Against Morphine-Heroine Addiction | INSTITUTO MACIONAL DE PSIQUIATRIA RAMON DE LA FUENTE MUNIZ (MX) | 2008-10-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080241183-A1 | Process For The Preparation And Use Of A Bivalent Vaccine Against Morphine-Heroine Addiction | OPRM1, OPRK1, OPRD1 | SLC6A5 2142/4885PAOX 2705/4885KDM4A 612/4885 |
| US-20110318381-A1 | PROCESS FOR THE PREPARATION AND USE OF A BIVALENT VACCINE AGAINST MORPHINE-HEROINE ADDICTION | OPRM1, OPRK1, OPRD1 | SLC6A5 2142/4885PAOX 2705/4885KDM4A 612/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.