SCHEMBL17723908

SCHEMBL17723908

COc1ccc(COC2(C(Cl)(Cl)Cl)CC2C)cc1

nearest known ligand 0.42

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 3/20 0.42
AGXT P21549 2/20 0.42
CMA1 P23946 1/20 0.39
APP P05067 4/20 0.38
MAOB P27338 1/20 0.37
SIGMAR1 Q99720 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10894103 0.68 IDO1 (0.55) IDO1AGXTCMA1APPMAOB
SCHEMBL16685865 0.67 IDO1 (0.42) IDO1AGXTAPP
SCHEMBL16685985 0.67 IDO1 (0.42) IDO1AGXTAPPMAOB
SCHEMBL16685993 0.66 IDO1 (0.41) IDO1AGXTAPPMAOB
SCHEMBL21107127 0.65 IDO1 (0.47) IDO1AGXTAPPMAOB
SCHEMBL1853891 0.65 IDO1 (0.61) IDO1AGXTCMA1APPMAOB
SCHEMBL6342 0.64 IDO1 (0.55) IDO1AGXTAPPMAOB
SCHEMBL34413 0.64 IDO1 (0.67) IDO1AGXTAPPMAOB
SCHEMBL31270 0.64 IDO1 (0.67) IDO1AGXTAPPMAOB
SCHEMBL24597253 0.64 IDO1 (0.50) IDO1AGXTAPPMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2016068220-A1 METHOD FOR PRODUCING EUSHEARILIDES 学校法人東京理科大学 2016-05-06 WO disclosed