Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.38 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | RECQL | P46063 | 2/20 | 0.37 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | PRKACA | P17612 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29466048 | 1.00 | KDM4E (0.50) | KDM4EATML3MBTL1MAPK1HTT | |
| SCHEMBL30951244 | 0.86 | KDM4E (0.53) | KDM4EATML3MBTL1MAPK1HTT | |
| SCHEMBL15835577 | 0.83 | MAPK1 (0.61) | KDM4EATML3MBTL1MAPK1HTT | |
| SCHEMBL31061815 | 0.83 | MAPK1 (0.61) | KDM4EATML3MBTL1MAPK1HTT | |
| SCHEMBL17723973 | 0.83 | MAPK1 (0.69) | KDM4EATML3MBTL1MAPK1HTT | |
| SCHEMBL17993382 | 0.83 | KDM4E (0.50) | KDM4EATML3MBTL1MAPK1HTT | |
| SCHEMBL15371684 | 0.82 | ESR1 (0.58) | KDM4EATML3MBTL1MAPK1HTT | |
| SCHEMBL24531917 | 0.82 | L3MBTL1 (0.75) | KDM4EATML3MBTL1MAPK1HTT | |
| SCHEMBL16573903 | 0.82 | L3MBTL1 (0.75) | KDM4EATML3MBTL1MAPK1HTT | |
| SCHEMBL21671314 | 0.82 | L3MBTL1 (0.75) | KDM4EATML3MBTL1MAPK1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109206422-B | Bipolar compound based on 1,3, 4-thiadiazole and preparation method and application thereof | 湖北尚赛光电材料有限公司 | 2022-03-18 | — | — | CN | disclosed |