Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 2/20 | 0.41 |
| ▸ | JAK2 | O60674 | 7/20 | 0.40 |
| ▸ | JAK1 | P23458 | 7/20 | 0.40 |
| ▸ | JAK3 | P52333 | 7/20 | 0.40 |
| ▸ | TYK2 | P29597 | 6/20 | 0.40 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.33 |
| ▸ | CSF1R | P07333 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | DRD1 | P21728 | 1/20 | 0.31 |
| ▸ | DRD5 | P21918 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17727981 | 0.73 | CEL (0.37) | DAOJAK2JAK1JAK3TYK2 | |
| SCHEMBL10590805 | 0.66 | DAO (0.36) | DAOJAK2JAK1JAK3TYK2 | |
| SCHEMBL13591096 | 0.62 | DAO (0.39) | DAO | |
| SCHEMBL21335045 | 0.62 | DAO (0.39) | DAO | |
| SCHEMBL6242097 | 0.62 | SMN1; SMN2 (0.46) | — | |
| SCHEMBL6241804 | 0.62 | SMN1; SMN2 (0.46) | — | |
| SCHEMBL19818980 | 0.60 | DAO (0.35) | DAO | |
| SCHEMBL20887773 | 0.60 | DAO (0.35) | DAO | |
| SCHEMBL6944629 | 0.60 | DAO (0.39) | DAOEPHX2 | |
| SCHEMBL1498646 | 0.60 | TDO2 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11155554-B2 | Rigid chiral redox-active isosceles triangular materials | NORTHWESTERN UNIVERSITY (US) | 2021-10-26 | — | — | US | disclosed |
| US-20190077804-A1 | RIGID CHIRAL REDOX-ACTIVE ISOSCELES TRIANGULAR MATERIALS | NORTHWESTERN UNIVERSITY (US) | 2019-03-14 | — | — | US | disclosed |
| EP-3429988-A1 | RIGID CHIRAL REDOX-ACTIVE ISOSCELES TRIANGULAR MATERIALS | Northwestern University (US) | 2019-01-23 | — | — | EP | disclosed |
| WO-2017161095-A1 | RIGID CHIRAL REDOX-ACTIVE ISOSCELES TRIANGULAR MATERIALS | NORTHWESTERN UNIVERSITY (US) | 2017-09-21 | — | — | WO | disclosed |
| US-9546169-B2 | Redox active triangular organic materials | NORTHWESTERN UNIVERSITY (US) | 2017-01-17 | — | — | US | disclosed |
| US-20160130271-A1 | REDOX ACTIVE TRIANGULAR ORGANIC MATERIALS | NORTHWESTERN UNIVERSITY | 2016-05-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160130271-A1 | REDOX ACTIVE TRIANGULAR ORGANIC MATERIALS | MT-ND1, NQO1, GPX4 | DAO 483/4885JAK2 3383/4885JAK1 1594/4885 |
| US-11155554-B2 | Rigid chiral redox-active isosceles triangular materials | GPX1, PRDX3, NQO1 | DAO 1081/4885JAK2 3320/4885JAK1 4051/4885 |
| US-20190077804-A1 | RIGID CHIRAL REDOX-ACTIVE ISOSCELES TRIANGULAR MATERIALS | GPX1, PRDX3, NQO1 | DAO 1081/4885JAK2 3320/4885JAK1 4051/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.