Known targets — ChEMBL curated mechanism
GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BHMGCRMMP1MMP13MMP7MMP8PTGS1PTGS2ileSpolrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Zinc Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7253675 | 0.94 | — | — | |
| Zinc Ion SCHEMBL1774073 | 0.94 | — | — | |
| Zinc Ion SCHEMBL2550126 | 0.94 | — | — | |
| SCHEMBL1322903 | 0.89 | — | — | |
| Zinc Ion SCHEMBL7570147 | 0.89 | — | — | |
| Zinc Ion SCHEMBL987037 | 0.89 | — | — | |
| SCHEMBL17289528 | 0.89 | — | — | |
| Water SCHEMBL6549354 | 0.89 | — | — | |
| SCHEMBL30507 | 0.88 | — | — | |
| SCHEMBL3577 | 0.88 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2714055-B1 | BIOCOMPATIBLE MATERIAL AND USES THEREOF | UNIV SYDNEY (AU) | 2019-09-04 | — | — | EP | claimed |
| US-9220806-B2 | Biocompatible material and uses thereof | THE UNIVERSITY OF SYDNEY (AU) | 2015-12-29 | — | — | US | claimed |
| US-8765163-B2 | Biocompatible material and uses thereof | THE UNIVERSITY OF SYDNEY (AU) | 2014-07-01 | — | — | US | claimed |
| WO-2012162753-A1 | BIOCOMPATIBLE MATERIAL AND USES THEREOF | THE UNIVERSITY OF SYDNEY (AU) | 2012-12-06 | — | — | WO | claimed |
| US-20110111005-A1 | BIOCOMPATIBLE MATERIAL AND USES THEREOF | THE UNIVERSITY OF SYDNEY (AU) | 2011-05-12 | — | — | US | claimed |
| WO-2010003191-A1 | BIOCOMPATIBLE MATERIAL AND USES THEREOF | THE UNIVERSITY OF SYDNEY (AU) | 2010-01-14 | — | — | WO | claimed |
| CN-107149698-B | Biocompatible materials and uses thereof | 阿莱格拉骨科有限公司 | 2021-01-15 | — | — | CN | disclosed |
| CN-110650709-A | Synthetic implantable stent | 悉尼大学 | 2020-01-03 | — | — | CN | disclosed |
| US-20190343985-A1 | A SYNTHETIC IMPLANTABLE SCAFFOLD | THE UNIVERSITY OF SYDNEY (AU) | 2019-11-14 | — | — | US | disclosed |
| EP-3562437-A1 | A SYNTHETIC IMPLANTABLE SCAFFOLD | Commercial Development & Industry Partnerships (AU) | 2019-11-06 | — | — | EP | disclosed |
| EP-2714055-B1 | BIOCOMPATIBLE MATERIAL AND USES THEREOF | UNIV SYDNEY (AU) | 2019-09-04 | — | — | EP | disclosed |
| WO-2018119493-A1 | A SYNTHETIC IMPLANTABLE SCAFFOLD | Commercial Development & Industry Partnerships (AU) | 2018-07-05 | — | — | WO | disclosed |
| US-9220806-B2 | Biocompatible material and uses thereof | THE UNIVERSITY OF SYDNEY (AU) | 2015-12-29 | — | — | US | disclosed |
| US-8765163-B2 | Biocompatible material and uses thereof | THE UNIVERSITY OF SYDNEY (AU) | 2014-07-01 | — | — | US | disclosed |
| WO-2012162753-A1 | BIOCOMPATIBLE MATERIAL AND USES THEREOF | THE UNIVERSITY OF SYDNEY (AU) | 2012-12-06 | — | — | WO | disclosed |
| US-20110111005-A1 | BIOCOMPATIBLE MATERIAL AND USES THEREOF | THE UNIVERSITY OF SYDNEY (AU) | 2011-05-12 | — | — | US | disclosed |
| WO-2010003191-A1 | BIOCOMPATIBLE MATERIAL AND USES THEREOF | THE UNIVERSITY OF SYDNEY (AU) | 2010-01-14 | — | — | WO | disclosed |