Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.39 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.39 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.39 |
| ▸ | AGXT | P21549 | 1/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2874123 | 0.81 | NOS1 (0.44) | ALDH1A1MEN1MAPTHTTKMT2A | |
| SCHEMBL2874120 | 0.81 | NOS1 (0.44) | ALDH1A1MEN1MAPTHTTKMT2A | |
| SCHEMBL17454827 | 0.78 | MGLL (0.42) | MAOAALDH1A1PRSS1PRSS2PRSS3 | |
| SCHEMBL13754834 | 0.78 | MAOA (0.41) | MAOAALDH1A1PRSS1PRSS2PRSS3 | |
| SCHEMBL296846 | 0.78 | — | — | |
| SCHEMBL498740 | 0.78 | — | — | |
| SCHEMBL296845 | 0.78 | — | — | |
| SCHEMBL3181549 | 0.77 | MAOA (0.48) | MAOAALDH1A1PRSS1PRSS2PRSS3 | |
| Hydrochloric Acid SCHEMBL11330484 | 0.76 | ALDH1A1 (0.61) | MAOAALDH1A1MEN1MAPTHTT | |
| SCHEMBL18065735 | 0.76 | KMT2A (0.52) | AGXTMEN1MAPTKMT2ATAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9334242-B2 | Compounds for treatment of cancer | GTX, INC. (US) | 2016-05-10 | — | — | US | disclosed |