Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMIGD3 | P0DMS9 | 4/20 | 0.62 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.62 |
| ▸ | CASP3 | P42574 | 2/20 | 0.62 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.62 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.62 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.62 |
| ▸ | STAT1 | P42224 | 1/20 | 0.62 |
| ▸ | NPC1 | O15118 | 8/20 | 0.60 |
| ▸ | RAB9A | P51151 | 8/20 | 0.60 |
| ▸ | MEN1 | O00255 | 5/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.59 |
| ▸ | PKM | P14618 | 3/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17732647 | 0.80 | NPC1 (0.63) | TMIGD3ADORA1CASP3SENP8SENP7 | |
| SCHEMBL3049854 | 0.77 | ADORA1 (1.00) | TMIGD3ADORA1CASP3SENP8SENP7 | |
| SCHEMBL1270133 | 0.76 | SMN1; SMN2 (0.75) | NPC1RAB9AMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL10253097 | 0.75 | RAB9A (1.00) | NPC1RAB9AMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL25422408 | 0.75 | HDAC2 (0.55) | TMIGD3ADORA1CASP3SENP8SENP7 | |
| SCHEMBL30464306 | 0.75 | HDAC2 (0.55) | TMIGD3ADORA1CASP3SENP8SENP7 | |
| SCHEMBL14516657 | 0.75 | HDAC1 (0.57) | TMIGD3ADORA1CASP3SENP8SENP7 | |
| SCHEMBL10253049 | 0.74 | NPC1 (0.57) | NPC1RAB9AMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL20769725 | 0.74 | RAB9A (0.65) | TMIGD3ADORA1CASP3SENP8SENP7 | |
| SCHEMBL16688465 | 0.74 | RAB9A (1.00) | NPC1RAB9AMEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9333193-B2 | Compositions and methods for treating tuberculosis | UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) | 2016-05-10 | — | — | US | disclosed |