Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC2 | Q92769 | 4/20 | 0.55 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.55 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.55 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.55 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.55 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.55 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.55 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.55 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.55 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.55 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.55 |
| ▸ | TMIGD3 | P0DMS9 | 4/20 | 0.51 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.51 |
| ▸ | STAT1 | P42224 | 1/20 | 0.51 |
| ▸ | CASP3 | P42574 | 1/20 | 0.51 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.51 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.51 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.51 |
| ▸ | F10 | P00742 | 1/20 | 0.48 |
| ▸ | DHPS | P49366 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25422408 | 1.00 | HDAC2 (0.55) | HDAC2HDAC1HDAC3HDAC4HDAC7 | |
| SCHEMBL27208733 | 0.76 | HDAC2 (0.54) | HDAC2HDAC1HDAC3HDAC4HDAC7 | |
| SCHEMBL30050486 | 0.76 | HDAC2 (0.54) | HDAC2HDAC1HDAC3HDAC4HDAC7 | |
| SCHEMBL13359266 | 0.76 | MAPK14 (0.59) | HDAC2HDAC1HDAC3HDAC4HDAC7 | |
| SCHEMBL17732532 | 0.75 | TMIGD3 (0.62) | HDAC2HDAC1HDAC3HDAC4HDAC7 | |
| SCHEMBL25715808 | 0.74 | RAB9A (0.53) | RAB9AMAPK14 | |
| SCHEMBL30464286 | 0.74 | RAB9A (0.53) | RAB9AMAPK14 | |
| SCHEMBL29874896 | 0.73 | HDAC1 (1.00) | HDAC2HDAC1HDAC3HDAC4HDAC7 | |
| SCHEMBL999904 | 0.73 | HDAC1 (1.00) | HDAC2HDAC1HDAC3HDAC4HDAC7 | |
| SCHEMBL17552176 | 0.72 | MAPT (0.59) | HDAC2HDAC1HDAC3HDAC4HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023111005-A1 | CARBOXAMIDE SUBSTITUTED HETEROAROMATIC COMPOUNDS FOR TREATING CANCER | WMT AG (DE) | 2023-06-22 | — | — | WO | disclosed |