Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | TDO2 | P48775 | 1/20 | 0.36 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 4/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8938037 | 0.82 | HTT (0.41) | ALDH1A1LMNAMEN1KMT2AGAA | |
| SCHEMBL22410447 | 0.70 | IDO1 (0.53) | ALDH1A1MAPK1IDO1TDO2MAOB | |
| SCHEMBL4438842 | 0.69 | ACHE (0.52) | ALDH1A1MAPK1NPC1GAAMAPT | |
| SCHEMBL30549337 | 0.68 | ALDH1A1 (0.46) | ALDH1A1MAPK1IDO1TDO2MEN1 | |
| SCHEMBL4103278 | 0.68 | ALDH1A1 (0.46) | ALDH1A1MAPK1IDO1TDO2MEN1 | |
| SCHEMBL11863314 | 0.68 | LMNA (0.41) | ALDH1A1LMNARAPGEF4MEN1KMT2A | |
| SCHEMBL16308853 | 0.68 | LMNA (0.41) | ALDH1A1LMNARAPGEF4MEN1KMT2A | |
| SCHEMBL16308862 | 0.68 | LMNA (0.41) | ALDH1A1LMNARAPGEF4MEN1KMT2A | |
| SCHEMBL16308856 | 0.68 | LMNA (0.41) | ALDH1A1LMNARAPGEF4MEN1KMT2A | |
| SCHEMBL642404 | 0.67 | IDO1 (0.48) | ALDH1A1MAPK1IDO1TDO2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8580395-B2 | Electroluminescent polymers, method for the production thereof, and use thereof | MERCK PATENT GMBH (DE) | 2013-11-12 | — | — | US | disclosed |
| US-20110108824-A1 | ELECTROLUMINESCENT POLYMERS, METHOD FOR THE PRODUCTION THEREOF, AND USE THEREOF | MERCK PATENT GMBH (DE) | 2011-05-12 | — | — | US | disclosed |