Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | NT5E | P21589 | 1/20 | 0.42 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | ESRRB | O95718 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | ESRRA | P11474 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | PLG | P00747 | 1/20 | 0.41 |
| ▸ | PLAU | P00749 | 1/20 | 0.41 |
| ▸ | PLAT | P00750 | 1/20 | 0.41 |
| ▸ | DHODH | Q02127 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3499138 | 0.86 | NT5E (0.51) | LMNAHSP90AB1KDM4ENT5EMAPKAPK2 | |
| SCHEMBL829490 | 0.85 | LMNA (0.72) | LMNAKDM4ECYP3A4CYP2C19HIF1A | |
| SCHEMBL17734602 | 0.81 | ESR1 (0.51) | LMNAHSP90AB1KDM4EHIF1ANT5E | |
| SCHEMBL10824124 | 0.78 | LMNA (0.72) | LMNAHSP90AB1NT5EALDH1A1ESRRB | |
| SCHEMBL19618608 | 0.78 | NT5E (0.44) | KDM4ENT5EALDH1A1ESRRBESR1 | |
| SCHEMBL20851781 | 0.77 | KDM4E (0.39) | LMNAHSP90AB1KDM4ECYP3A4CYP2C19 | |
| SCHEMBL14690472 | 0.77 | LMNA (0.56) | LMNAHSP90AB1KDM4ECYP3A4CYP2C19 | |
| SCHEMBL20851773 | 0.76 | ALDH1A1 (0.51) | LMNAHSP90AB1KDM4ECYP3A4CYP2C19 | |
| SCHEMBL7059007 | 0.76 | KDM4E (0.58) | LMNAKDM4ECYP3A4CYP2C19HIF1A | |
| SCHEMBL8899425 | 0.76 | KDM4E (0.53) | LMNAHSP90AB1KDM4EMAPKAPK2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10033001-B2 | Organic electroluminescent compound and organic electroluminescent device comprising the same | ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) | 2018-07-24 | — | — | US | disclosed |
| US-10033001-B2 | Organic electroluminescent compound and organic electroluminescent device comprising the same | ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) | 2018-07-24 | — | — | US | disclosed |
| US-20170317297-A1 | ORGANIC ELECTROLUMINESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME | DUPONT SPECIALTY MATERIALS KOREA LTD (KR) | 2017-11-02 | — | — | US | disclosed |
| US-20170317297-A1 | ORGANIC ELECTROLUMINESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME | DUPONT SPECIALTY MATERIALS KOREA LTD (KR) | 2017-11-02 | — | — | US | disclosed |
| WO-2016072780-A1 | ORGANIC ELECTROLUMINESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME | ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) | 2016-05-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10033001-B2 | Organic electroluminescent compound and organic electroluminescent device comprising the same | EPCAM, SOD1, ICOSLG | LMNA 3158/4885HSP90AB1 790/4885KDM4E 1306/4885 |
| US-20170317297-A1 | ORGANIC ELECTROLUMINESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME | EPCAM, SOD1, ICOSLG | LMNA 3158/4885HSP90AB1 790/4885KDM4E 1306/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.