Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.72 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | ELANE | P08246 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 5/20 | 0.42 |
| ▸ | BCHE | P06276 | 4/20 | 0.42 |
| ▸ | GRIN1 | Q05586 | 4/20 | 0.42 |
| ▸ | GRIN2A | Q12879 | 4/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | NQO2 | P16083 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14690472 | 0.87 | LMNA (0.56) | LMNAKDM4EMAPTALDH1A1CYP3A4 | |
| SCHEMBL17734598 | 0.85 | LMNA (0.54) | LMNAKDM4EMAPTALDH1A1CYP3A4 | |
| SCHEMBL30572382 | 0.84 | LMNA (1.00) | LMNAKDM4EMAPTALDH1A1ELANE | |
| SCHEMBL4768081 | 0.84 | LMNA (1.00) | LMNAKDM4EMAPTALDH1A1ELANE | |
| SCHEMBL2538787 | 0.84 | KDM4E (0.66) | LMNAKDM4EMAPTALDH1A1CYP3A4 | |
| SCHEMBL32474876 | 0.84 | LMNA (0.52) | LMNAKDM4EMAPTALDH1A1CYP3A4 | |
| SCHEMBL7695488 | 0.84 | LMNA (0.52) | LMNAKDM4EMAPTALDH1A1CYP3A4 | |
| Hydrochloric Acid SCHEMBL9494656 | 0.82 | LMNA (0.96) | LMNAKDM4EMAPTALDH1A1ELANE | |
| SCHEMBL9494320 | 0.82 | LMNA (0.64) | LMNAKDM4EMAPTALDH1A1CYP3A4 | |
| SCHEMBL19689622 | 0.81 | LMNA (0.68) | LMNAKDM4EMAPTALDH1A1ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118027026-A | Pyrido six-membered ring compounds and application thereof | 南京宁丹新药技术有限公司 | 2024-05-14 | — | — | CN | disclosed |
| US-11873291-B2 | Quinoline cGAS antagonist compounds | IMMUNESENSOR THERAPEUTICS, INC. (US) | 2024-01-16 | — | — | US | disclosed |
| CN-116964050-A | Compounds useful as T cell activators | 戈萨默生物服务公司 | 2023-10-27 | — | — | CN | disclosed |
| EP-4262986-A1 | COMPOUNDS USEFUL AS T CELL ACTIVATORS | Gossamer Bio Services, Inc. (US) | 2023-10-25 | — | — | EP | disclosed |
| US-20230271954-A1 | COMPOUNDS USEFUL AS T CELL ACTIVATORS | GOSSAMER BIO SERVICES INC (US) | 2023-08-31 | — | — | US | disclosed |
| US-20230271954-A1 | COMPOUNDS USEFUL AS T CELL ACTIVATORS | GOSSAMER BIO SERVICES INC (US) | 2023-08-31 | — | — | US | disclosed |
| US-20230271954-A1 | COMPOUNDS USEFUL AS T CELL ACTIVATORS | GOSSAMER BIO SERVICES INC (US) | 2023-08-31 | — | — | US | disclosed |
| US-RE49481-E1 | Compounds for the treatment and prophylaxis of respiratory syncytial virus disease | HOFFMANN-LA ROCHE INC. (US) | 2023-04-04 | — | — | US | disclosed |
| WO-2022133083-A1 | COMPOUNDS USEFUL AS T CELL ACTIVATORS | GOSSAMER BIO SERVICES, INC. (US) | 2022-06-23 | — | — | WO | disclosed |
| WO-2022133083-A1 | COMPOUNDS USEFUL AS T CELL ACTIVATORS | GOSSAMER BIO SERVICES, INC. (US) | 2022-06-23 | — | — | WO | disclosed |
| WO-2008024423-A2 | 4-THIO SUBSTITUTED QUINOLINE AND NAPHTHYRIDINE COMPOUNDS | XTL BIOPHARMACEUTICALS LTD. (US) | 2008-02-28 | — | — | WO | disclosed |
| WO-2007087250-A2 | TRICYCLIC INHIBITORS OF 5-LIPOXYGENASE | AMIRA PHARMACEUTICALS, INC. (US) | 2007-08-02 | — | — | WO | disclosed |
| US-20070060595-A1 | Novel fused heterocyclic compound and use thereof | ONO PHARMACEUTICAL CO., LTD. (JP) | 2007-03-15 | — | — | US | disclosed |
| EP-1671962-A1 | NOVEL FUSED HETEROCYCLIC COMPOUND AND USE THEREOF | ONO PHARMACEUTICAL CO., LTD. (JP) | 2006-06-21 | — | — | EP | disclosed |
| WO-2002026713-A1 | ANTIPARASITIC COMPOUNDS | KING'S COLLEGE LONDON (GB) | 2002-04-04 | — | — | WO | disclosed |
| US-6320051-B1 | AMINO(NH) OR OXYGEN(O) SUBSTITUTED, ENZYME INHIBITORS OF STAPHLOCCOCUS AUREUS METHIONYL T-RNA SYNTHETASE (MRS); ANTIBACTERIAL AGENTS | SMITHKLINE BEECHAM PLC (GB) | 2001-11-20 | — | — | US | disclosed |
| EP-1084110-A1 | QUINOLONES USED AS MRS INHIBITORS AND BACTERICIDES | SMITHKLINE BEECHAM PLC (GB) | 2001-03-21 | — | — | EP | disclosed |
| WO-1999055677-A1 | QUINOLONES USED AS MRS INHIBITORS AND BACTERICIDES | SMITHKLINE BEECHAM PLC (GB) | 1999-11-04 | — | — | WO | disclosed |
| US-5112837-A | Inhibitors of thymidylate synthetase enzyme | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-05-12 | — | — | US | disclosed |
| EP-0318225-A2 | 6-Aryl aminomethyl quinoline derivatives and their use as anti-tumour agents | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1989-05-31 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230271954-A1 | COMPOUNDS USEFUL AS T CELL ACTIVATORS | DGKZ, DGKA, DGKG | LMNA 1800/4885KDM4E 3666/4885MAPT 3016/4885 |
| US-11873291-B2 | Quinoline cGAS antagonist compounds | CGAS, GLS2, GLS | LMNA 1681/4885KDM4E 4338/4885MAPT 3235/4885 |
| US-20070060595-A1 | Novel fused heterocyclic compound and use thereof | JUN, CHUK, RELA | LMNA 4382/4885KDM4E 1873/4885MAPT 4634/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.